ICO Subspecialty and Residency Curricula

Documents for Comment

XVII. APPENDIX Part 2b


References Sections XI-XVI

 

International Council of Ophthalmology

Residency Curriculum 2011

 

References for each curriculum section have been updated in the 2011 Residency Curriculum. Evidence-based medicine, in which therapeutic decisions are based on documented, verifiable, and validated information, is an increasingly important educational framework upon which physicians should make recommendations for their patients. Whenever possible, updated references and sources of knowledge providing such information should receive precedence and preference by both teachers and students of clinical ophthalmology. Links to the practice of evidence-based medicine can be found at www.aao.org. 

 






XI. Vitreoretinal Diseases

Branch Vein Occlusion Studies (BVOS)
1. Branch Vein Occlusion Study Group. Argon laser scatter photocoagulation for prevention of neovascularization and vitreous hemorrhage in branch vein occlusion. A randomized clinical trial. Branch Vein Occlusion Study Group. Arch Ophthalmol 1986; 104: 34-41.
2. The Branch Vein Occlusion Study Group. Argon laser photocoagulation for macular edema in branch vein occlusion. The Branch Vein Occlusion Study Group. Am J Ophthalmol 1984; 98: 271-282.
3. Brown GC, Brown MM, Sharma S, Busbee B, Brown H. Incremental cost-effectiveness of laser therapy for visual loss secondary to branch retinal vein occlusion. Ophthalmic Epidemiol 2002; 9:1-10.
4. Campochiaro PA, Heier JS, Feiner L, Gray S, Saroj N, Rundle AC, Murahashi WY,  Rubio RG; BRAVO Investigators. Ranibizumab for macular edema following branch retinal vein occlusion: six-month primary end point results of a phase III study. Ophthalmology. 2010 Jun;117(6):1102-1112.
5. Brown DM, Campochiaro PA, Bhisitkul RB, Ho AC, Gray S, Saroj N, Adamis AP, Rubio RG, Murahashi WY. Sustained benefits from Ranibizumab for macular edema following branch retinal vein occlusion: 12-month outcomes of a phase III study. Ophthalmology. 2011 Jun 17. [Epub ahead of print]

Additional Background Reading
1. Barbazetto IA, Schmidt-Erfurth UM. Evaluation of functional defects in branch retinal vein occlusion before and after laser treatment with scanning laser perimetry. Ophthalmology 2000; 107: 1089 -1098.
2. Saxena S. Laser photocoagulation in retinal vein occlusion: branch vein occlusion study and central vein occlusion study recommendations. Indian J Ophthalmol 1997; 45: 125 -128. Comment: 1997;45:261 -262.
3. Cousins SW, Flynn HW Jr., Clarkson JG. Macroaneurysms associated with retinal branch vein occlusion. Am J Ophthalmol 1990;109:567-570.
4. Finkelstein D. Argon laser photocoagulation for macular edema in branch vein occlusion. Ophthalmology 1986; 93: 975 ¬977.
5. (No authors listed). Branch vein occlusion study. Invest Ophthalmol Vis Sci 1979;18:1097.

Macular Photocoagulation Study (MPS)
1. Macular Photocoagulation Study Group. Risk factors for choroidal neovascularization in the second eye of patients with juxtafoveal or subfoveal choroidal neovascularization secondary to age-related macular degeneration. Macular Photocoagulation Study Group. Arch Ophthalmol 1997;115:741-747.
2. Macular Photocoagulation Study Group. Laser photocoagulation for juxtafoveal choroidal neovascularization. Five-year results from randomized clinical trials. Macular Photocoagulation Study Group. Arch Ophthalmol 1994;112:500-509.
3. Macular Photocoagulation Study Group. Five-year follow-up of fellow eyes of patients with age-related macular degeneration and unilateral extrafoveal choroidal neovascularization. Macular Photocoagulation Study Group. Arch Ophthalmol 1993;111:1189-1199.
4. Macular Photocoagulation Study Group. Laser photocoagulation of subfoveal neovascular lesions of age-related macular degeneration. Updated findings from two clinical trials. Macular Photocoagulation Study Group. Arch Ophthalmol 1993;111:1200-1209.
5. Macular Photocoagulation Study Group. Argon laser photocoagulation for neovascular maculopathy. Five-year results from randomized clinical trials. Macular Photocoagulation Study Group. Arch Ophthalmol1991;109:1109-1114.
6. Macular Photocoagulation Study Group. Krypton laser photocoagulation for neovascular lesions of age-related macular degeneration. Results of a randomized clinical trial. Macular Photocoagulation Study Group. Arch Ophthalmol 1990;108:816-82.
7. Macular Photocoagulation Study Group. Persistent and recurrent neovascularization after krypton laser photocoagulation for neovascular lesions of age-related macular degeneration. Macular Photo-coagulation Study Group. Arch Ophthalmol 1990;108:825-831.
8. Bressler SB, Maguire MG, Bressler NM, Fine SL. Relationship of drusen and abnormalities of the retinal pigment epithelium to the prognosis of neovascular macular degeneration. The Macular Photocoagulation Study Group. Arch Ophthalmol 1990; 108: 1442 -1447.
9. Chamberlin JA, Bressler NM, Bressler SB et al. The use of fundus photographs and fluorescein angiograms in the identification and treatment of choroidal neovascularization in the Macular Photocoagulation Study. The Macular Photocoagulation Study Group. Ophthalmology 1989; 96: 1526 -1534.
10. Macular Photocoagulation Study Group. Krypton laser photocoagulation for neovascular lesions of ocular histoplasmosis. Results of a randomized clinical trial. Macular Photocoagulation Study Group. Arch Ophthalmol 1987;105:1499-1507.
11. Macular Photocoagulation Study Group. Recurrent choroidal neovascularization after argon laser photocoagulation for neovascular maculopathy. Macular Photocoagulation Study Group. Arch Ophthalmol 1986;104:503-512.
12. Macular Photocoagulation Study Group. Argon laser photocoagulation for neovascular maculopathy. Three-year results from randomized clinical trials. Macular Photocoagulation Study Group. Arch Ophthalmol 1986;104:694-701.
13. Macular Photocoagulation Study Group. Argon laser photocoagulation for ocular histoplasmosis. Results of a randomized clinical trial. Arch Ophthalmol 1983;101:1347-1357.
14. Macular Photocoagulation Study Group. Argon laser photocoagulation for idiopathic neovascularization. Results of a randomized clinical trial. Arch Ophthalmol 1983;101:1358-1361.
15. (No authors listed). Argon laser photocoagulation for senile macular degeneration. Results of a randomized clinical trial. Arch Ophthalmol 1982; 100: 912-918.
16. Zimmer-Galler IE, Bressler NM, Bressler SB. Treatment of choroidal neovascularization: updated information from recent macular photocoagulation study group reports. Int Ophthalmol Clin 1995;35:37-57.

Additional Background Reading
1. Macular Photocoagulation Study Group. Occult choroidal neovascularization. Influence on visual outcome in patients with age-related macular degeneration. Macular Photocoagulation Study Group. Arch Ophthalmol 1996;114:400-412.
2. Macular Photocoagulation Study Group. Five-year follow-up of fellow eyes of individuals with ocular histoplasmosis and unilateral extrafoveal or juxtafoveal choroidal neovascularization. Macular Photocoagulation Study Group. Arch Ophthalmol 1996;114: 677-688.
3. Macular Photocoagulation Study Group. Laser photocoagulation for neovascular lesions nasal to the fovea. Results from clinical trials for lesions secondary to ocular histoplasmosis or idiopathic causes. Macular Photocoagulation Study Group. Arch Ophthalmol 1995;113:56-61.
4. Macular Photocoagulation Study Group. The influence of treatment extent on the visual acuity of eyes treated with Krypton laser for juxtafoveal choroidal neovascularization. Macular Photocoagulation Study Group. Arch Ophthalmol 1995;113:190-194.
5. Macular Photocoagulation Study Group. Persistent and recurrent neovascularization after laser photocoagulation for subfoveal choroidal neovascularization of age-related macular degeneration. Macular Photocoagulation Study Group. Arch Ophthalmol 1994;112:489-499.
6. Macular Photocoagulation Study Group. Evaluation of argon green vs krypton red laser for photocoagulation of subfoveal choroidal neovascularization in the macular photocoagulation study. Macular Photocoagulation Study (MPS) Group. Arch Ophthalmol 1994;112:11761-1184.
7. Orr PR, Blackhurst DW, Hawkins BS. Patient and clinic factors predictive of missed visits and inactive status in a multicenter clinical trial. The Macular Photocoagulation Study Group. Control Clin Trials 1992; 13:40-49.
8. Bressler NM, Bressler SB, Alexander J et al. Loculated fluid. A previously undescribed fluorescein angiographic finding in choroidal neovascularization associated with macular degeneration. Macular Photocoagulation Study Reading Center. Arch Ophthalmol 1991; 109:211-215.
9. Macular Photocoagulation Study Group. Laser photocoagulation of subfoveal neovascular lesions in age-related macular degeneration. Results of a randomized clinical trial. Macular Photocoagulation Study Group. Arch Ophthalmol 1991;109:1220 -1231.
10. Macular Photocoagulation Study Group. Laser photocoagulation of subfoveal recurrent neovascular lesions in age-related macular degeneration. Results of a randomized clinical trial. Macular Photocoagulation Study Group. Arch Ophthalmol 1991;109:1232-1241.
11. Macular Photocoagulation Study Group. Subfoveal neovascular lesions in age-related macular degeneration. Guidelines for evaluation and treatment in the macular photocoagulation study. Macular Photocoagulation Study Group. Arch Ophthalmol 1991; 109:1242-1257.
12. Hawkins BS, Prior MJ, Fisher MR, Blackhurst DW. Relationship between rate of patient enrollment and quality of clinical center performance in two multicenter trials in ophthalmology. Control Clin Trials 1990;11:374-394.
13. Macular Photocoagulation Study Group. Krypton laser photocoagulation for idiopathic neovascular lesions. Results of a randomized clinical trial. Macular Photocoagulation Study Group. Arch Ophthalmol 1990;108:832-837.
14. Blackhurst DW, Maguire MG. Reproducibility of refraction and visual acuity measurement under a standard protocol. The Macular Photocoagulation Study Group. Retina 1989;9:163-169.
15. Macular Photocoagulation Study Group. Persistent and recurrent neovascularization after krypton laser photocoagulation for neovascular lesions of ocular histoplasmosis. Macular Photocoagulation Study Group. Arch Ophthalmol 1989;107:344-352.
16. Fine SL. Early detection of extrafoveal neovascular membranes by daily central field evaluation. Ophthalmology 1985;92:603-609.
17. Macular Photocoagulation Study Group .Changing the protocol: a case report from the Macular Photocoagulation Study. Macular Photocoagulation Study Group. Control Clin Trials 1984;5:203-216.
18. Gottfredsdottir MS, Sverrisson T, Musch DC, Stefansson E. Age related macular degeneration in monozygotic twins and their spouses in Iceland. Acta Ophthalmol Scand 1999;77:422-425.
19. Macular Photocoagulation Study Group. Age-related macular degeneration. The Macular Photocoagulation Study. Am J Ophthalmol 1984;98:376-377.
20. Freund KB, Yannuzzi LA, Sorenson JA. Age-related macular degeneration and choroidal neovascularization. Am J Ophthalmol 1993;115:786-791.
21. Jampol LM. Hypertension and visual outcome in the macular photocoagulation study. Arch Ophthalmol 1991;109:789-790.
22. Jost BF, Alexander MF, Maguire MG et al. Laser treatment for choroidal neovascularization outside randomized clinical trials. Arch Ophthalmol 1988;106:357-361.
23. Fine SL. Macular photocoagulation study. Arch Ophthalmol 1980;98: 832.
24. Fine SL, Hawkins B, Maguire M. Macular photocoagulation study. Arch Ophthalmol 1984; 102:1583.
25. Jampol LM, Tielsch J. Race, macular degeneration, and the Macular Photocoagulation Study. Arch Ophthalmol 1992; 110: 1699-1700.
26. Moisseiev J, Alhalel A, Masuri R, Treister G. The impact of the macular photocoagulation study results on the treatment of exudative age-related macular degeneration. Arch Ophthalmol 1995; 113: 185 -189.
27. Beatty S, Au Eong KG, McLeod D, Bishop PN. Photocoagulation of subfoveal choroidal neovascular membranes in age related macular degeneration: the impact of the macular photocoagulation study in the United Kingdom and Republic of Ireland.Br J Ophthalmol 1999; 83:1103 -1104.
28. Custis PH, Bressler SB, Bressler NM. Laser management of subfoveal choroidal neovascularization in age-related maculardegeneration. Curr Opin Ophthalmol1993; 4: 7-18.
29. Dyer DS, Bressler SB, Bressler NM. The role of laser wavelength in the treatment of vitreoretinal diseases. Curr Op in Ophthalmol 1994; 5: 35-43.
30. Bergink GJ, Deutman AF, van den Broek JF, van Daal WA, van der Maazen RW. Radiation therapy for subfoveal choroidal neovascular membranes in age-related macular degeneration. A pilot study. Graefes Arch Clin Exp Ophthalmol 1994;232:591-598.
31. Gelfand YA, Linn S, Miller B. The application of the macular photocoagulation study eligibility criteria for laser treatment in age-related macular degeneration. Ophthalmic Surg Lasers 1997;28:823-827.
32. Spaide RF, Guyer DR, McCormick B et al. External beam radiation therapy for choroidal neovascularization. Ophthalmology 1998;105:24-30
33. Ormerod LD, Puklin JE, Frank RN. Long-term outcomes after the surgical removal of advanced subfoveal neovascular membranes in age-related macular degeneration. Ophthalmology1994;101:1201-1210.
34. Avvad FK, Duker JS, Reichel E, Margolis TI, Puliafito CA. The digital indocyanine green videoangiography characteristics of well-defined choroidal neovascularization. Ophthalmology 1995;102:401-405.
35. Yannuzzi LA. A new standard of care for laser photocoagulation of subfoveal choroidal neovascularization secondary to age-related macular degeneration. Data revisited. Arch Ophthalmol 1994;112 462-464.
36. Tiedeman JS. Treatment of subfoveal choroidal neovascularization. Arch Ophthalmol 1995; 113:137-138.
37. Hawkins WR. Visual prognosis of eyes with submacular choroidal neovascularization. Arch Ophthalmol 1994; 112: 874 -875.
38. Fine SL, Hawkins BS, Maguire MG. Krypton Laser photocoagulation for neovascular lesions of age-related macular degeneration. Arch Ophthalmol 1991; 109: 614-615.
39. Tornambe PE, Poliner LS. Partial ablation of neovascular membranes involving the fovea. Arch Ophthalmol 1989;107: 955-956.
40. Wolfe JA, Horton MB, McAteer MB, Szuter CF, Clayton T. Race, macular degeneration, and diabetic maculopathy. Arch Ophthalmol 1993; 111: 1603 -1604.
41. Chakravarthy U, Hart P, Finger P. External beam radiation therapy for CNV. Ophthalmology 1998; 105:1790-1791; author reply 1791 -1792 Beaumont P, Chang A. External beam radiation therapy for CNV. Ophthalmology 1998; 105: 1792 -1793; author reply 1793 -1794.
42. Schachat AP. Management of subfoveal choroidal neovascularization. Arch Ophthalmol 1991; 109:1217-1218.

Age-Related Eye Disease Study (AREDS)
1. Clemons TE, Chew EY, Bressler SB, McBee W. National Eye Institute Visual Function questionnaire in the Age-Related Eye Disease Study (AREDS): AREDS Report No. 10. Arch Ophthalmol 2003; 121: 211-217.
2. Age-Related Eye Disease Study Research Group. The effect of five-year zinc supplementation on serum zinc, serum cholesterol and hematocrit in persons randomly assigned to treatment group in the age-related eye disease study: AREDS Report No. 7.J Nutr 2002; 132: 697-702.
3. Age-Related Eye Disease Study Research Group. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E and beta carotene for age-related cataract and vision loss: AREDS report no. 9. Arch Ophthalmol 2001; 119: 1439-1452.
4. Age-Related Eye Disease Study Research Group. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8. Arch Ophthalmol 2001; 119: 1417-1436.
5. Age-Related Eye Disease Study Research Group. The Age-Related Eye Disease Study system for classifying age-related macular degeneration from stereoscopic color fundus photographs: the Age-Related Eye Disease Study Report Number 6. Am J Ophthalmol 2001; 132: 668-681.
6. Age-Related Eye Disease Study Research Group. The age-related eye disease study (AREDS) system for classifying cataracts from photographs: AREDS report no. 4. Am J Ophthalmol 2001; 131: 167-175.
7. (No authors listed). Risk factors associated with age-related nuclear and cortical cataract: a case-control study in the Age-Related Eye Disease Study, AREDS Report No. 5. Ophthalmology 2001; 108:1400-1408.
8. (No authors listed). The Age-Related Eye Disease Study: a clinical trial of zinc and antioxidants -Age-Related Eye Disease Study Report No. 2. J Nutr 2000; 130: 1516S -1519S.
9. (No authors listed). Risk factors associated with age-related macular degeneration. A case-control study in the age-related eye disease study: Age-Related Eye Disease Study Report Number 3. Ophthalmology 2000; 107: 2224-2232.
10. (No authors listed). The Age-Related Eye Disease Study (AREDS): design implications. AREDS report no. 1. Control Clin Trials 1999; 20: 573-600.

AMD Studies
1. Chang TS, Bressler NM, Fine JT, Dolan CM, Ward J, Klesert TR; MARINA Study Group. Improved vision-related function after ranibizumab treatment of neovascular age-related macular degeneration: results of a randomized clinical trial. Arch Ophthalmol. 2007 Nov;125(11):1460-9.
2. Kaiser PK, Brown DM, Zhang K, Hudson HL, Holz FG, Shapiro H, Schneider S, Acharya NR. Ranibizumab for predominantly classic neovascular age-related macular degeneration: subgroup analysis of first-year ANCHOR results. Am J Ophthalmol. 2007 Dec;144(6):850-857.
3. Bressler NM, Chang TS, Suñer IJ, Fine JT, Dolan CM, Ward J, Ianchulev T; MARINA and ANCHOR Research Groups. Vision-related function after ranibizumab treatment by better- or worse-seeing eye: clinical trial results from MARINA and ANCHOR. Ophthalmology. 2010 Apr;117(4):747-56.
4. Rosenfeld PJ, Shapiro H, Tuomi L, Webster M, Elledge J, Blodi B; MARINA and ANCHOR Study Groups. Characteristics of patients losing vision after 2 years of monthly dosing in the phase III ranibizumab clinical trials. Ophthalmology. 2011 Mar;118(3):523-30.
5. CATT Research Group, Martin DF, Maguire MG, Ying GS, Grunwald JE, Fine SL, Jaffe GJ. Ranibizumab and bevacizumab for neovascular age-related macular degeneration. N Engl J Med. 2011 May 19;364(20):1897-908.
6. Martin DF, Maguire MG, Fine SL, Ying GS, Jaffe GJ, Grunwald JE, Toth C, Redford M, Ferris FL 3rd; Comparison of Age-related Macular Degeneration Treatments Trials (CATT) ResearchGroup Writing Committee. Ranibizumab and Bevacizumab for Treatment of Neovascular Age-Related Macular Degeneration: Two-Year Results. Ophthalmology. 2012 May 1. [Epub ahead of print].

Vertoporfin in Photodynamic Therapy (VIP)
1. Blinder KJ, Blumenkranz MS, Bressler NM et al. Verteporfin therapy of subfoveal choroidal neovascularization in pathologic myopia: 2-year results of a randomized clinical trial –VIP report no.3. Ophthalmology 2003; 110:667-673.
2. Verteporfin in Photodynamic Therapy Study Group. Verteporfin therapy of subfoveal choroidal neovascularization in age-related macular degeneration: two-year results of a randomized clinical trial including lesions with occult with no classic choroidal neovascularization -verteporfin in photo-dynamic therapy report 2. Am J Ophthalmol 2001; 131: 541-560.
3. Verteporfin in Photodynamic Therapy Study Group. Photodynamic therapy of subfoveal choroidal neovascularization in pathologic myopia with verteporfin. 1-year results of a randomized clinical trial -VIP report no. 1. Ophthalmology 2001; 108: 841-852.
4. Verteporfin Roundtable 2000 and 2001 Participants, Treatment of age-related macular degeneration with photodynamic therapy (TAP) study group principal investigators, Verteporfin in photodynamic therapy (VIP) study group principal investigators. Guidelines for using verteporfin (visudyne) in photodynamic therapy to treat choroidal neovascularization due to age-related macular degeneration and othercauses. Retina 2002; 22:6-18.

Treatment of Age-Related Macular Degeneration with Photodynamic Therapy (TAP)
1. Blumenkranz MS, Bressler NM, Bressler SB et al. Verteporfin therapy for subfoveal choroidal neovascularization in age-related macular degeneration: three-year results of an open-label extension of 2 randomized clinical trials -TAP Report no. 5. Arch Ophthalmol 2002; 120: 1307-1314.
2. Rubin GS, Bressler NM. Effects of verteporfin therapy on contrast on sensitivity: Results From the Treatment of Age-Related Macular Degeneration With Photodynamic Therapy (TAP) investigation-TAP report No 4. Retina 2002; 22: 536¬544.
3. Bressler NM, Arnold J, Benchaboune M et al. Verteporfin therapy of subfoveal choroidal neovascularization in patients with age-related macular degeneration: additional information regarding baseline lesion composition's impact on vision outcomes-TAP report No. 3. Arch Ophthalmol 2002; 120: 1443-1454.
4. Bressler NM. Photodynamic therapy of subfoveal choroidal neovascularization in age-related macular degeneration with verteporfin: two-year results of 2 randomized clinical trials-tap report 2. Arch Ophthalmol 2001; 119: 198-207.
5. Miller JW, Schmidt-Erfurth U, Sickenberg M et al. Photodynamic therapy with verteporfin for choroidal neovascularization caused by age-related macular degeneration: results of a single treatment in a phase 1 and 2 study. Arch Ophthalmol 1999; 117: 1161-1173 [Erratumin: Arch Ophthalmol 2000 Apr; 1118: 1488].
6. (No authors listed). Photodynamic therapy of subfoveal choroidal neovascularization in age-related macular degeneration with verteporfin: one-year results of 2 randomized clinical trials -TAP report. Treatment of age-related macular degeneration with photodynamic therapy (TAP) Study Group. Arch Ophthalmol 1999; 117:1329-1345 [Erratum in: Arch Ophthalmol 2000 April; 1118: 1488].

Silicone Study
1. Abrams GW, Azen SP, McCuen BW, 2nd et al. Vitrectomy with silicone oil or long-acting gas in eyes with severe proliferative vitreoretinopathy: results of additional and long-term follow-up. Silicone Study report 11. Arch Ophthalmol 1997; 115: 335-344.
2. McCuen BW, 2nd, Azen SP, Stern W et al. Vitrectomy with silicone oil or perfluoropropane gas in eyes with severe proliferative vitreoretinopathy. Silicone Study Report 3. Retina 1993; 13: 279 -284.
3. (No authors listed). Vitrectomy with silicone oil or sulfur hexafluoride gas in eyes with severe proliferative vitreoretinopathy: results of a randomized clinical trial. Silicone Study Report 1. Arch Ophthalmol 1992; 110:770-779.
4. (No authors listed). Krypton laser photocoagulation for neovascular lesions of ocular histoplasmosis. Results of a randomized clinical trial. Macular Photocoagulation Study Group. Arch Ophthalmol 1987; 105: 1499-1507.
5. (No authors listed). Vitrectomy with silicone oil or perfluoropropane gas in eyes with severe proliferative vitreoretinopathy: results of a randomized clinical trial. Silicone Study Report 2. Arch Ophthalmol 1992; 110: 780 -792.
6. Lean JS, Stern WH, Irvine AR, Azen SP. Classification of proliferative vitreoretinopathy used in the silicone study. The Silicone Study Group. Ophthalmology 1989; 96: 765-771.
7. Brown GC, Brown MM, Sharma S, Busbee B, Landy J. A cost-utility analysis of interventions for severe proliferative vitreoretinopathy. Am J Ophthalmol 2002; 133:365-372.
8. Pastor JC. Proliferative vitreoretinopathy: an overview. Surv Ophthalmol 1998; 43:3 -18.

Additional Background Reading
1. Diddie KR, Azen SP, Freeman HM et al. Anterior proliferative vitreoretinopathy in the silicone study. Silicone Study Report Number10. Ophthalmology1996; 103:1092 -1099 Lean J, Azen SP, Lopez PF et al. The prognostic utility of the Silicone Study Classification System. Silicone Study Report 9. Silicone Study Group . Arch Ophthalmol 1996; 114:286-292.
2. Abrams GW, Azen SP, Barr CC et al. The incidence of corneal abnormalities in the Silicone Study. Silicone Study Report 7. Arch Ophthalmol 1995; 113: 764-769.
3. Cox MS, Azen SP, Barr CC et al. Macular pucker after successful surgery for proliferative vitreoretinopathy. Silicone Study Report 8. Ophthalmology 1995; 102: 1884-1891.
4. Hutton WL, Azen SP, Blumenkranz MS et al. The effects of silicone oil removal. Silicone Study Report 6. Arch Ophthalmol 1994; 112: 778-785.
5. Peyman GA, Greve MD, Millsap CM. Silicone oil vs perfluoropropane gas as a postoperative retinal tamponade. Arch Ophthalmol 1994; 112: 728 -729; Reply by McCuen BW, Azen SP: 729.
6. Chan CK. Reports by the Silicone Study Group. Arch Ophthalmol 1993; 111: 428; author reply 429 Le Mer Y. Reports by the Silicone Study Group. Arch Ophthalmol 1993; 111: 429.
7. Barr CC, Lai MY, Lean JS et al. Postoperative intraocular pressure abnormalities in the Silicone Study. Silicone Study Report 4. Ophthalmology 1993; 100: 1629 -1635.
8. Blumenkranz MS, Azen SP, Aaberg T et al. Relaxing retinotomy with silicone oil or long-acting gas in eyes with severe proliferative vitreoretinopathy. Silicone Study Report 5. The Silicone Study Group. Am J Ophthalmol 1993; 116: 557-564.
9. Azen SP, Boone DC, Barlow W et al. Methods, statistical features, and baseline results of a standardized, multicentered ophthalmologic surgical trial: the Silicone Study. Control Clin Trials 1991; 12: 438-455.
10. Barlow W, Azen S. The effect of therapeutic treatment crossovers on the power of clinical trials. The Silicone Study Group. Control Clin Trials 1990; 11: 314 -326
11. Azen SP, Irvine AR, Davis MD et al. The validity and reliability of photographic documentation of proliferative vitreoretinopathy. Ophthalmology 1989; 96:352-357.
12. Boone DC, Lai M, Azen S, Silicone Study Group. Clinical judgment and centralized data management. Control Clin Trials 1989: 339.
13. Irvine AR. Photographic documentation and grading of PVR, in Freeman HM, Tolentino FI (eds). Proliferative Vitreoretinopathy, New York, Springer-Verlag 1989: 105-109.
14. Stern WH, Lean JS, Silicone Study Group. Intraocular silicone oil versus gas in the management of proliferative vitreoretinopathy (PVR): A multicenter clinical study, in Freeman HM, Tolentino FI (eds). Proliferative Vitreoretinopathy. New York, Springer-Verlag, 1989.
15. Glaser BM. Silicone oil for proliferative vitreoretinopathy. Does it help or hinder? Arch Ophthalmol 1988; 106:323-324.
16. Lean JS. Changing attitudes in United States to use of intravitreal silicone. Jpn J Ophthalmol 1987; 31: 132-137.
17. (No authors listed). Proliferative vitreoretinopathy (editorial). The Silicone Study Group. Am J Ophthalmol 1985; 99: 593-595.
18. Campochiaro PA. The Silicone Study. A small piece of the PVR puzzle is put into place. Arch Ophthalmol 1997; 115: 407-408.
19. Haller JA, Campochiaro PA. Oil and gas on troubled waters. The proliferative vitreoretinopathy studies. Arch Ophthalmol 1992; 110: 768 -769.

Submacular Surgery Trials (SST)
1. Bressler NM, Hawkins BS, Sternberg P Jr., McDonald HR. Are the submacular surgery trials still relevant in an era of photo dynamic therapy? Ophthalmology 2001; 108: 435-436.
2. Grossniklaus HE, Green WR. Histopathologic and ultrastructural findings of surgically excised choroidal neovascularization. Submacular Surgery Trials Research Group. Arch Ophthalmol 1998; 116: 745-749.

Additional Background Reading
1. Bressler NM, Bressler SB, Hawkins BS et al. Submacular surgery trials randomized pilot trial of laser photocoagulation versus surgery for recurrent choroidal neovascularization secondary to age-related macular degeneration: I. Ophthalmic outcomes submacular surgery trials pilot study report number 1. Am J Ophthalmol 2000; 130:  387-407.
2. photocoagulation versus surgery for recurrent choroidal neovascularization secondary to age-related macular degeneration: II. Quality of life outcomes submacular surgery trials pilot study report number 2. Am J Ophthalmol 2000; 130: 408 -418.
3. Bressler NM. Submacular surgery. New information, more questions. Arch Ophthalmol 1997;115:1071-1072.
4. Bressler NM. Submacular surgery. Are randomized trials necessary? Arch Ophthalmol 1995;113:1557-1560.
5. Dong LM, Hawkins BS, Marsh MJ. Consistency between visual acuity scores obtained at different test distances: theory vs observations in multiple studies. Arch Ophthalmol 2002; 120:1523-1533.
6. Orr PR, Cramer LD, Hawkins BS, Bressler NM. Manifest refraction versus autorefraction for patients with subfoveal choroidal neovascularization. Invest Ophthalmol Vis Sci 2001;42:447-452.
7. Fleckner MR, Hochman MA, Buzney SM et al. Complications of surgery for subfoveal choroidal neovascularization. Int Ophthalmol Clin 2000;40:201-214.
8. Uemura A. [Subretinal surgery for choroidal neovascularization]. Nippon Ganka Gakkai Zasshi 2000;104:611-620.
9. Rao PK, Thomas MA. Update on surgical removal of choroidal neovascularization. Curr Op in Ophthalmol 2000;11:180-185.

Multicenter Trial of Cryotherapy for Retinopathy of Prematurity (CRYO-ROP)
1. (No authors listed). Multicenter Trial of Cryotherapy for Retinopathy of Prematurity: ophthalmological outcomes at 10 years. Arch Ophthalmol 2001; 119: 1110 -1118.
2. Repka M., Palmer EA, Tung B. Involution of retinopathy of prematurity. Cryotherapy for Retinopathy of Prematurity Cooperative Group. Arch Ophthalmol 2000; 118:645-649.
3. Saunders RA, Donahue ML, Christmann LM et al. Racial variation in retinopathy of prematurity. The Cryotherapy for Retinopathy of Prematurity Cooperative Group. Arch Ophthalmol 1997; 115: 604-608.
4. Bartholomew PA, Chao J, Evans JL et al. Acceptance/Use of the Teller acuity card procedure in the clinic. Am Orthoptic J 1996; 46: 100-106.
5. Quinn GE, Dobson V, Barr CC et al. Visual acuity of eyes after vitrectomy for retinopathy of prematurity: follow-up at 5 1/2 years. The Cryotherapy for Retinopathy of Prematurity Cooperative Group. Ophthalmology 1996; 103: 595-600.
6. (No authors listed). Multicenter trial of cryotherapy for retinopathy of prematurity: natural history ROP: ocular outcome at 5(1/2) years in premature infants with birth weights less than 1251 g. Arch Ophthalmol 2002; 120: 595-599.
7. Dobson V, Quinn GE, Summers CG, Hardy RJ, Tung B; Cryotherapy for Retinopathy of Prematurity Cooperative Group. Visual acuity at 10 years in Cryotherapy for Retinopathy of Prematurity (CRYO-ROP) study eyes: effect of retinal residua of retinopathy of prematurity. Arch Ophthalmol. 2006 Feb;124(2):199-202.
8. Msall ME, Phelps DL, Hardy RJ, Dobson V, Quinn GE, Summers CG, Tremont MR; Cryotherapy for Retinopathy of Prematurity Cooperative Group. Educational and social competencies at 8 years in children with threshold retinopathy of prematurity in the CRYO-ROP multicenter study. Pediatrics. 2004 Apr;113(4):790-9.

Additional Background Reading
1. (No authors listed). Contrast sensitivity at age 10 years in children who had threshold retinopathy of prematurity. Arch Ophthalmol 2001; 119: 1129 -1133.
2. (No authors listed). Effect of retinal ablative therapy for threshold retinopathy of prematurity: results of Goldmann perimetry at the age of 10 years. Arch Ophthalmol 2001; 119: 1120 -1125.
3. Quinn GE, Dobson V, Siatkowski R et al. Does cryotherapy affect refractive error? Results from treated versus control eyes in the cryotherapy for retinopathy of prematurity trial. Ophthalmology 2001; 108: 343 -347.
4. Msall ME, Phelps DL, DiGaudio KM et al. Severity of neonatal retinopathy of prematurity is predictive of neurodevelopmental functional outcome at age 5.5 years. Behalf of the Cryotherapy for Retinopathy of Prematurity Cooperative Group. Pediatrics 2000; 106: 998 -1005.
5. Dobson V, Quinn GE, Siatkowski RM et al. Agreement between grating acuity at age 1 year and Snellen acuity at age 5.5 years in the preterm child. Cryotherapy for Retinopathy of Prematurity Cooperative Group. Invest Ophthalmol Vis Sci 1999;40: 496 -503.
6. Harvey EM, Dobson V, Tung B, Quinn GE, Hardy RJ. Interobserver agreement for grating acuity and letter acuity assess¬ment in 1-to 5.5-year-olds with severe retinopathy of prematurity. Invest Ophthalmol Vis Sci 1999; 40: 1565 -1576.
7. GE, Dobson V, Kivlin J et al. Prevalence of myopia between 3 months and 5 1/2 years in preterm infants with and without retinopathy of prematurity. Cryotherapy for Retinopathy of Prematurity Cooperative Group. Ophthalmology 1998; 105: 1292 -1300.
8. Bremer DL, Palmer EA, Fellows RR et al. Strabismus in premature infants in the first year of life. Cryotherapy for Retinopathy of Prematurity Cooperative Group. Arch Ophthalmol 1998; 116: 329-333.
9. Repka M, Summers CG, Palmer EA et al. The incidence of ophthalmologic interventions in children with birth weights less than 1251 grams. Results through 5 1/2 years. Cryotherapy for Retinopathy of Prematurity Cooperative Group. Ophthalmology 1998; 105: 1621 -1627.
10. Hardy RJ, Palmer EA, Schaffer DB et al. Outcome-based management of retinopathy of prematurity. Multicenter Trial of Cryotherapy for Retinopathy of prematurity Cooperative Group.JAapos1997; 1:46-54.
11. (No authors listed). Multicenter trial of cryotherapy for reti¬nopathy of prematurity. Snellen visual acuity and structural outcome at 5 1/2 years after randomization. Cryotherapy for Retinopathy of Prematurity Cooperative Group. Arch Ophthalmol 1996; 114: 417 -424.
12. Dobson V, Quinn GE, Abramov I et al. Color vision measured with pseudoisochromatic plates at five-and-a-half years in eyes of children from the CRYO-ROP study. Invest Ophthalmol VisSci 1996; 37: 2467-2474.
13. Gilbert WS, Quinn GE, Dobson V et al. Partial retinal detachment at 3 months after threshold retinopathy of prematurity. Long-term structural and functional outcome. Multicenter Trial of Cryotherapy for Retinopathy of Prematurity Cooperative Group. Arch Ophthalmol 1996; 114: 1085 -1091.
14. Kivlin JD, Biglan AW, Gordon RA et al. Early retinal vessel development and iris vessel dilatation as factors in retinopathy of prematurity. Cryotherapy for Retinopathy of Prematurity (CRYO-ROP) Cooperative Group. Arch Ophthalmol 1996; 114: 150 -154.
15. GE, Dobson V, Hardy RJ et al. Visual fields measured with double-arc perimetry in eyes with threshold retinopathy of prematurity from the cryotherapy for retinopathy of prematurity trial. The CRYO-Retinopathy of Prematurity Cooperative Group. Ophthalmology 1996; 103: 1432 -1437.
16. Dobson V, Quinn GE, Saunders RA et al. Grating visual acuity in eyes with retinal residua of retinopathy of prematurity. The Cryotherapy for Retinopathy of Prematurity Cooperative Group.ArchOphthalmol 1995; 113:1172-1177.
17. Dobson V, Quinn GE, Tung B, Palmer EA, Reynolds JD. Comparison of recognition and grating acuities in very-low-birthweight children with and without retinal residua of retinopathy of prematurity. Cryotherapy for Retinopathy of Prematurity Cooperative Group. Invest Ophthalmol Vis Sci 1995; 36: 692 -702.
18. Quinn GE, Dobson V, Biglan A et al. Correlation of retinopathy of prematurity in fellow eyes in the cryotherapy for retinopathy of prematurity study. The Cryotherapy for Retinopathy of Prematurity Cooperative Group. Arch Ophthalmol 1995; 113: 469 -473.
19. The natural ocular outcome of premature birth and retinopathy. Status at 1 year. Cryotherapy for Retinopathy of Prematurity Cooperative Group. Arch Ophthalmol 1994; 112: 903 -912.
20. Dobson V, Quinn GE, Summers CG et al. Effect of acute-phase retinopathy of prematurity on grating acuity development in the very low birth weight infant. The Cryotherapy for Retinopathy of Prematurity Cooperative Group. Invest Ophthalmol Vis Sci 1994; 35:4236 -4244.
21. Multicenter trial of cryotherapy for retinopathy of prematurity. 3 1/2-year outcome -structure and function. Cryotherapy for Retinopathy of Prematurity Cooperative Group. Arch Ophthalmol 1993; 111: 339-344.
22. Evans MS, Wallace PR, Palmer EA. Fundus Photography in small infants. J Ophthal Photography 1993; 15:38-39.
23. Reynolds J, Dobson V, Quinn GE et al. Prediction of visual function in eyes with mild to moderate posterior pole residua of retinopathy of prematurity. Cryotherapy for Retinopathy of Prematurity Cooperative Group. Arch Ophthalmol 1993; 111: 1050 -1056.
24. Schaffer DB, Palmer EA, Plotsky DF et al. Prognostic factors in the natural course of retinopathy of prematurity. The Cryotherapy for Retinopathy of Prematurity Cooperative Group. Ophthalmology 1993; 100: 230 -237.
25. Gilbert WS, Dobson V, Quinn GE et al. The correlation of visual function with posterior retinal structure in severe retinopathy of prematurity. Cryotherapy for Retinopathy of Prematurity Cooperative Group. Arch Ophthalmol 1992; 110: 625-631.
26. Quinn GE, Dobson V, Repka M et al. Development of myopia in infants with birth weights less than 1251 grams. The Cryotherapy for Retinopathy of Prematurity Cooperative Group. Ophthalmology 1992; 99: 329 -340.
27. Summers G, Phelps DL, Tung B, Palmer EA. Ocular cosmesis in retinopathy of prematurity. The Cryotherapy for Retinopathy of Prematurity Cooperative Group. Arch Ophthalmol 1992; 110: 1092 -1097.
28. Trueb L, Evans J, Hammel A, Bartholomew P, Dobson V. Assessing visual acuity of visually impaired children using the Teller acuity cards. Am Orthoptic J 1992; 2:149 -154.
29. Hardy RJ, Davis BR, Palmer EA, Tung B. Statistical considerations in terminating randomization in the Multicenter Trial of Cryotherapy for Retinopathy of Prematurity. Cryotherapy for Retinopathy of Prematurity Cooperative Group. Control Clin Trials 1991; 12: 293 -303.
30. Palmer EA, Flynn JT, Hardy RJ et al. Incidence and early course of retinopathy of prematurity. The Cryotherapy for Retinopathy of Prematurity Cooperative Group. Ophthalmology 1991; 98: 1628-1640.
31. Palmer EA, Hardy RJ, Davis BR et al. Operational aspects of terminating randomization in the Multicenter Trial of Cryotherapy for Retinopathy of Prematurity. Cryotherapy for Retinopathy of Prematurity Cooperative Group. Control Clin Trials 1991; 12: 277-292.
32. Phelps DL, Brown DR, Tung B et al. 28-day survival rates of 6676 neonates with birth weights of 1250 grams or less. Pediatrics 1991; 87: 7-17.
33. Quinn GE, Dobson V, Barr CC et al. Visual acuity in infants after vitrectomy for severe retinopathy of prematurity. Ophthalmology 1991; 98:5 -13.
34. (No authors listed). Multicenter trial of cryotherapy for reti¬nopathy of prematurity. Three-month outcome. Cryotherapy for Retinopathy of Prematurity Cooperative Group. Arch Ophthalmol 1990; 108:195 -204.
35. Dobson V, Quinn GE, Biglan AW et al. Acuity card assessment of visual function in the cryotherapy for retinopathy of pre-maturity trial. Invest Ophthalmol Vis Sci 1990; 31: 1702-1708.
36. Watzke RC, Robertson JE Jr., Palmer EA et al. Photographic grading in the retinopathy of prematurity cryotherapy trial. Arch Ophthalmol 1990; 108: 950 -955 Multicenter trial of cryotherapy for retinopathy of prematurity. Preliminary results.
37. Cryotherapy for Retinopathy of Prematurity Cooperative Group. Arch Ophthalmol 1988; 106: 471-479.
38. Multicenter trial of cryotherapy for retinopathy of prematurity: preliminary results. Cryotherapy for Retinopathy of Prematurity Cooperative Group. Pediatrics 1988; 81: 697-706.
39. Reynolds JD, Dobson V, Quinn GE et al. Evidence-based screening criteria for retinopathy of prematurity: natural history data from the CRYO-ROP and LIGHT-ROP studies. Arch Ophthalmol 2002; 120: 1470-1476.
40. Onofrey CB, Feuer WJ, Flynn JT. The outcome of retinopathy of prematurity: screening for retinopathy of prematurity using an outcome predictive program. Ophthalmology 2001; 108: 27-34; discussion 34 -35.
41. Clemett R, Darlow B. Results of screening low-birth-weight infants for retinopathy of prematurity. Curr Op in Ophthalmol 1999; 10: 155 -163.
42. (No authors listed). Multicenter trial of cryotherapy for reti¬nopathy of prematurity. One-year outcome - structure and function. Cryotherapy for Retinopathy of Prematurity Cooperative Group. Arch Ophthalmol 1990; 108:1408-1416.
43. Palmer EA. Results of U.S. randomized clinical trial of cryotherapy for ROP (CRYO-ROP). Doc Ophthalmol 1990; 74: 245-251.
44. Lutty GA, Chan-Ling T, Phelps DL, Adamis AP, Berns KI, Chan CK, Cole CH, D'Amore PA, Das A, Deng WT, Dobson V, Flynn JT, Friedlander M, Fulton A, Good WV, Grant MB, Hansen R, Hauswirth WW, Hardy RJ, Hinton DR, Hughes S, McLeod DS, Palmer EA, Patz A, Penn JS, Raisler BJ, Repka MX, Saint-Geniez M, Shaw LC, Shima  DT, Smith BT, Smith LE, Tahija SG, Tasman W, Trese MT. Proceedings of the Third International Symposium on Retinopathy of Prematurity: an update on ROP from the lab to the nursery (November 2003, Anaheim, California). Mol Vis. 2006 May 23;12:532-80.
45. Good WV, Hardy RJ, Dobson V, Palmer EA, Phelps DL, Quintos M, Tung B; Early Treatment for Retinopathy of Prematurity Cooperative Group. The incidence and course of retinopathy of prematurity: findings from the early treatment for retinopathy of prematurity study. Pediatrics. 2005 Jul;116(1):15-23.
46. Palmer EA, Hardy RJ, Dobson V, Phelps DL, Quinn GE, Summers CG, Krom CP, Tung  B; Cryotherapy for Retinopathy of Prematurity Cooperative Group. 15-year outcomes following threshold retinopathy of prematurity: final results from the multicenter trial of cryotherapy for retinopathy of prematurity. Arch Ophthalmol. 2005 Mar;123(3):311-8.
47. Jandeck C, Kellner U, Heimann H, Foerster MH. [Comparison of the anatomical and functional outcome after laser or cryotherapy for retinopathy of prematurity (ROP)]. Ophthalmologe. 2005 Jan;102(1):33-8.
48. Repka MX, Tung B, Good WV, Shapiro M, Capone A Jr, Baker JD, Barr CC, Phelps DL, van Heuven WA. Outcome of eyes developing retinal detachment during the Early Treatment for Retinopathy of Prematurity Study (ETROP). Arch Ophthalmol. 2006 Jan;124(1):24-30.
49. Jones JG, MacKinnon B, Good WV, Hardy RJ, Dobson V, Palmer EA, Phelps DL, Quintos M, Tung B; Early Treatment for Retinopathy of Prematurity Cooperative Group. The early treatment for ROP (ETROP) randomized trial: study results and nursing care adaptations. Insight. 2005 Apr-Jun;30(2):7-13. Review.
50. Final results of the Early Treatment for Retinopathy of Prematurity (ETROP) randomized trial. Good WV; Early Treatment for Retinopathy of Prematurity Cooperative Group. Trans Am Ophthalmol Soc. 2004;102:233-48; discussion 248-50.
51. Phelps DL; ETROP Cooperative Group. The Early Treatment for Retinopathy of Prematurity study: better outcomes, changing strategy. Pediatrics. 2004 Aug;114(2):490-1.

Central Vein Occlusion Study (CVOS)
1. The Central Vein Occlusion Study Group. Natural history and clinical management of central retinal vein occlusion. The Central Vein Occlusion Study Group. Arch Ophthalmol 1997;115:486-491.
2. The Central Vein Occlusion Study Group. Evaluation of grid pattern photocoagulation for macular edema in central vein occlusion. The Central Vein Occlusion Study Group M report. Ophthalmology 1995;102:1425-1433.
3. The Central Vein Occlusion Study Group. A randomized clinical trial of early pan-retinal photocoagulation for ischemic central vein occlusion. The Central Vein Occlusion Study Group N report. Ophthalmology 1995;102:1434 -1444.
4. Fekrat S, Finkelstein D. Current concepts in the management of central retinal vein occlusion. Curr Op in Ophthalmol 1997;8:50-54.
5. Haller JA, Bandello F, Belfort R Jr, Blumenkranz MS, Gillies M, Heier J, Loewenstein A, Yoon YH, Jacques ML, Jiao J, Li XY, Whitcup SM; OZURDEX GENEVA Study Group. Randomized, sham-controlled trial of dexamethasone intravitreal implant in patients with macular edema due to retinal vein occlusion. Ophthalmology. 2010 Jun;117(6):1134-1146.
6. Brown DM, Campochiaro PA, Singh RP, Li Z, Gray S, Saroj N, Rundle AC, Rubio RG, Murahashi WY; CRUISE Investigators. Ranibizumab for macular edema following central retinal vein occlusion: six-month primary end point results of a phase III study. Ophthalmology. 2010 Jun;117(6):1124-1133.
7. Ip MS, Scott IU, VanVeldhuisen PC, Oden NL, Blodi BA, Fisher M, Singerman LJ, mTolentino M, Chan CK, Gonzalez VH; SCORE Study Research Group. A randomized trial comparing the efficacy and safety of intravitreal triamcinolone with observation  to treat vision loss associated with macular edema secondary to central retinal vein occlusion: the Standard Care vs Corticosteroid for Retinal Vein Occlusion (SCORE) study report 5. Arch Ophthalmol. 2009 Sep;127(9):1101-14.
8. Scott IU, Ip MS, VanVeldhuisen PC, Oden NL, Blodi BA, Fisher M, Chan CK, Gonzalez VH, Singerman LJ, Tolentino M; SCORE Study Research Group. A randomized trial comparing the efficacy and safety of intravitreal triamcinolone with standard care to treat vision loss associated with macular Edema secondary to branch retinal vein occlusion: the Standard Care vs Corticosteroid for Retinal Vein Occlusion (SCORE) study report 6. Arch Ophthalmol. 2009 Sep;127(9):1115-28.
9. Chan CK, Ip MS, Vanveldhuisen PC, Oden NL, Scott IU, Tolentino MJ, Blodi BA; SCORE Study Investigator Group. SCORE Study Report #11 Incidences of neovascular events in eyes with retinal vein occlusion. Ophthalmology. 2011 Mar 25. [Epub ahead of print].

Additional Background Reading
1. Clarkson JG. Central Vein Occlusion Study: photographic protocol and early natural history. Trans Am Ophthalmol Soc 1994;92:203-213. Discussion 213-215.
2. (No authors listed). Baseline and early natural history report. The Central Vein Occlusion Study. Arch Ophthalmol 1993;111:1087-1095.
3. Soubrane G. Macular edema in retinal vein occlusion: up-date from the central retinal vein occlusion study. Doc Ophthalmol 1999;97:279 -281.

Diabetes Control and Complications Trial (DCCT)
1. (No authors listed). Lifetime benefits and costs of intensive therapy as practiced in the diabetes control and complications trial. The Diabetes Control and Complications Trial Research Group. Jama 1996; 276: 1409 -1415.
2. (No authors listed). The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group. N Engl J Med 1993; 329: 977-986.
3. (No authors listed). Progression of retinopathy with intensive versus conventional treatment in the Diabetes Control and Complications Trial. Diabetes Control and Complications Trial Research Group. Ophthalmology 1995; 102: 647 -661.
4. (No authors listed). Early worsening of diabetic retinopathy in the Diabetes Control and Complications Trial. Arch Ophthalmol 1998; 116: 874-886 [Erratum appears in Arch Ophthalmol 1998; 1116: 1469].
5. (No authors listed). The effect of intensive diabetes treatment on the progression of diabetic retinopathy in insulin-dependent diabetes mellitus. The Diabetes Control and ComplicationsTrial. Arch Ophthalmol 1995; 113:36-51.
6. Barr CC. Retinopathy and nephropathy in patients with type 1 diabetes four years after a trial of intensive therapy. The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group. N Engl J Med 2000; 342: 381 -389.
7. Eastman RC, Javitt JC, Herman WH et al. Model of complications of NIDDM. II. Analysis of the health benefits and cost-effectiveness of treating NIDDM with the goal of normoglycemia. Diabetes Care 1997; 20: 735-744.
8. Klein R, Klein BE. Relation of glycemic control to diabetic complications and health outcomes. Diabetes Care 1998; 21, Suppl 3: C39 -43.

Additional Background Reading
1. Peterson KA, Smith CK. The DCCT findings and standards of care for diabetes. Am Fam Physician 1995; 52: 1092 -1098.
2. Leiter LA. Use of bioelectrical impedance analysis measurements in patients with diabetes. The Diabetes Control and Complications Trial Research Group. Am J Clin Nutr 1996; 64: 515S -518S.
3. (No authors listed). Epidemiology of severe hypoglycemia in the diabetes control and complications trial. The DCCT Research Group. Am J Med 1991; 90:450 -459.
4. (No authors listed). Effect of intensive therapy on residual beta-cell function in patients with type 1 diabetes in the diabetes control and complications trial. A randomized, controlled trial. The Diabetes Control and Complications Trial Research Group. Ann Intern Med 1998; 128: 517 -523.
5. (No authors listed). The effect of intensive diabetes therapy on the development and progression of neuropathy. The Diabetes Control and Complications Trial Research Group. Ann Intern Med 1995; 122:561 -568.
6. (No authors listed). Color photography vs fluorescein angiography in the detection of diabetic retinopathy in the diabetes control and complications trial. The Diabetes Control and Complications Trial Research Group. Arch Ophthalmol 1987; 105: 1344-1351.
7. Worrall G. Results of the DCCT trial. Implications for managing our patients with diabetes. Can Fam Physician 1994; 40: 1955-1960, 1963 -1965.
8. Hoogwerf BJ, Brouhard BH. Glycemic control and complications of diabetes mellitus: practical implications of the Diabetes Control and Complications Trial (DCCT). Cleve Clin J Med 1994; 61:34-37; quiz 80 -82.
9. (No authors listed). Feasibility of centralized measurements of glycated hemoglobin in the Diabetes Control and Complications Trial: a multicenter study. The DCCT Research Group. Clin Chem 1987; 33: 2267-2271.
10. (No authors listed). Implementation of a multicomponent process to obtain informed consent in the Diabetes Control and Complications Trial. The DCCT Research Group. Control Clin Trials 1989; 10: 83-96.
11. (No authors listed). Clustering of long-term complications in families with diabetes in the diabetes control and complications trial. The Diabetes Control and Complications Trial Research Group. Diabetes 1997; 46: 1829-1839.
12. (No authors listed). Factors in development of diabetic neuropathy. Baseline analysis of neuropathy in feasibility phase of Diabetes Control and Complications Trial (DCCT). The DCCT Research Group. Diabetes 1988; 37: 476-481.
13. (No authors listed). Hypoglycemia in the Diabetes Control and Complications Trial. The Diabetes Control and Complications Trial Research Group. Diabetes 1997; 46: 271 -286.
14. Monnier VM, Bautista O, Kenny D et al. Skin collagen glyca¬tion, glycoxidation, and crosslinking are lower in subjects with long-term intensive versus conventional therapy of type 1 diabetes: relevance of glycated collagen products versus HbA1c as markers of diabetic complications. DCCT Skin Collagen Ancillary Study Group. Diabetes Control and Complications Trial. Diabetes 1999; 48: 870-880.
15. (No authors listed). The Diabetes Control and Complications Trial (DCCT). Design and methodologic considerations for the feasibility phase. The DCCT Research Group. Diabetes 1986; 35: 530 -545.
16. Gautier JF, Beressi JP, Leblanc H, Vexiau P, Passa P. Are the implications of the Diabetes Control and Complications Trial (DCCT) feasible in daily clinical practice? Diabetes Metab 1996; 22: 415 -419.
17. McCulloch DK, Glasgow RE, Hampson SE, Wagner E. A systematic approach to diabetes management in the post-DCCT era. Diabetes Care 1994; 17: 765-769.
18. Moses RG, Rodgers DV, Griffiths RD. Clinic variations hold important clues to the understanding and implementation of the DCCT results. Diabetes Care 1996; 19: 178-180.
19. Dagogo-Jack S. DCCT results and diabetes care in developing countries. Diabetes Care 1995; 18: 416 -417.
20. (No authors listed). Diabetes Control and Complications Trial (DCCT): results of feasibility study. The DCCT Research Group. Diabetes Care 1987; 10: 1-19.
21. (No authors listed). Diabetes Control and Complications Trial (DCCT). Update. DCCT Research Group. Diabetes Care 1990; 13: 427-433.
22. (No authors listed). Effect of pregnancy on microvascular complications in the diabetes control and complications trial. The Diabetes Control and Complications Trial Research Group. Diabetes Care 2000; 23: 1084 -1091.
23. Orchard TJ. From diagnosis and classification to complications and therapy. DCCT. Part II Diabetes Control and Complications Trial. Diabetes Care 1994; 17: 326-338.
24. Thompson CJ, Cummings JF, Chalmers J, Gould C, Newton RW. How have patients reacted to the implications of the DCCT? Diabetes Care 1996; 19: 876 -879.
25. Rubin RR, Peyrot M. Implications of the DCCT. Looking beyond tight control. Diabetes Care 1994; 17: 235 -236.
26. (No authors listed). Lipid and lipoprotein levels in patients with IDDM diabetes control and complication. Trial experience. The DCCT Research Group. Diabetes Care 1992; 15: 886 -894.
27. (No authors listed). Reliability and validity of a diabetes quality-of-life measure for the diabetes control and complications trial (DCCT). The DCCT Research Group. Diabetes Care 1988; 11: 725 -732.
28. Harris MI, Eastman RC, Siebert C. The DCCT and medical care for diabetes in the U.S. Diabetes Care 1994; 17:761-764.
29. (No authors listed). Weight gain associated with intensive therapy in the diabetes control and complications trial. The DCCT Research Group. Diabetes Care 1988; 11: 567 -573.
30. (No authors listed). AADE position statement: Diabetes Control and Complications Trial (DCCT). Diabetes Educ 1994; 20: 106, 108.
31. Ahern JA, Kruger DF, Gatcomb PM, Petit WA Jr., Tamborlane WV. The diabetes control and complications trial (DCCT): the trial coordinator perspective. Report by the DCCT Research Group. Diabetes Educ 1989; 15: 236-241.
32. Ahern J, Grove N, Strand T et al. The impact of the Trial Coordinator in the Diabetes Control and Complications Trial (DCCT). The DCCT Research Group. Diabetes Educ 1993; 19: 509 -512.
33. Ahern JA, Ramchandani N, Cooper J et al. Using a primary nurse manager to implement DCCT recommendations in a large pediatric program. Diabetes Educ 2000; 26: 990-994.
34. Molyneaux LM, Constantino MI, McGill M, Zilkens R, Yue DK. Better glycaemic control and risk reduction of diabetic complications in Type 2 diabetes: comparison with the DCCT. Diabetes Res Clin Pract 1998; 42:77-83.
35. (No authors listed). Implementing the lessons of DCCT. Report of a national workshop under the auspices of the British Diabetic Association. Diabet Med 1994; 11: 220 -228.
36. Gibb I, Parnham AJ, Lord C et al. Standardization of glycated haemoglobin assays throughout the Northern region of England: a pilot study. Diabet Med 1997; 14: 584-588.
37. (No authors listed). The effect of intensive diabetes therapy on measures of autonomic nervous system function in the Diabetes Control and Complications Trial (DCCT). Diabetologia 1998; 41:416 -423.
38. Zinman B. Translating the Diabetes Control and Complications Trial (DCCT) into clinical practice: overcoming the barriers. Diabetologia 1997; 40 Suppl 2: S88 -90.
39. Szucs TD, Smala AM, Fischer T. [Costs of intensive insulin therapy in type 1 diabetes mellitus]. Experiences from the DCCT study. Fortschr Med 1998; 116:34 -38.
40. German Leiter LA, Lukaski HC, Kenny DJ et al. The use of bioelectrical impedance analysis (BIA) to estimate body composition in the Diabetes Control and Complications Trial (DCCT). Int J Obes Relat Metab Disord 1994; 18: 829 -835.
41. Purnell J, Hokanson JE, Marcovina SM et al. Effect of excessive weight gain with intensive therapy of type 1 diabetes on lipid levels and blood pressure: results from the DCCT. Diabetes Control and Complications Trial. Jama 1998; 280: 140-146 [Erratum appears in JAMA 1998 1994; 1280:1841].
42. (No authors listed). A screening algorithm to identify clinically significant changes in neuropsychological functions in the Diabetes Control and Complications Trial. DCCT Research Group. J Clin Exp Neuropsychol 1994;16: 303-316.
43. (No authors listed). Effects of age, duration and treatment of insulin-dependent diabetes mellitus on residual beta-cell function: observations during eligibility testing for the Diabetes Control and Complications Trial (DCCT). The DCCT Research Group. J Clin Endocrinol Metab 1987; 65: 30 -36.
44. White NH, Cleary PA, Dahms W et al. Beneficial effects of intensive therapy of diabetes during adolescence: outcomes after the conclusion of the Diabetes Control and Complications Trial (DCCT). J Pediatr 2001; 139: 804 -812.
45. (No authors listed). Effect of intensive diabetes treatment on the development and progression of long-term complications in adolescents with insulin-dependent diabetes mellitus: Diabetes Control and Complications Trial. Diabetes Control and Complications Trial Research Group. J Pediatr 1994; 125: 177 -188.
46. Moses R, Rodgers D, Griffiths R. Diabetic control and hypoglycaemia in the Illawarra area of NSW, Australia: a comparison with the DCCT. J Qual Clin Pract 1995; 15: 89-97.
47. Delahanty L, Simkins SW, Camelon K. Expanded role of the dietitian in the Diabetes Control and Complications Trial: implications for clinical practice. The DCCT Research Group. J Am Diet Assoc 1993; 93:758-764,767.
48. Anderson EJ, Richardson M, Castle G et al. Nutrition interventions for intensive therapy in the Diabetes Control and Complications Trial. The DCCT Research Group. J Am Diet Assoc 1993; 93: 768 -772.
49. Schmidt LE, Cox MS, Buzzard IM, Cleary PA. Reproducibility of a comprehensive diet history in the Diabetes Control and Complications Trial. The DCCT Research Group. J Am Diet Assoc 1994; 94: 1392 -1397.
50. Levey AS, Greene T, Schluchter MD et al. Glomerular filtration rate measurements in clinical trials. Modification of Diet in Renal Disease Study Group and the Diabetes Control and Complications Trial Research Group. J Am Soc Nephrol 1993; 4: 1159 -1171.
51. Molitch ME, Steffes MW, Cleary PA, Nathan DM. Baseline analysis of renal function in the Diabetes Control and Complications Trial. The Diabetes Control and Complications Trial Research Group [corrected]. Kidney Int 1993; 43: 668 -674.
52. (No authors listed). Effect of intensive therapy on the devel¬opment and progression of diabetic nephropathy in the Diabetes Control and Complications Trial. The Diabetes Control and Complications (DCCT) Research Group. Kidney Int 1995; 47: 1703-1720.
53. Covic AM, Schelling JR, Constantiner M, Iyengar SK, Sedor JR. Serum C-peptide concentrations poorly phenotype type 2 diabetic end-stage renal disease patients. Kidney Int 2000; 58: 1742-1750.
54. Chrisholm DJ. The Diabetes Control and Complications Trial (DCCT). A milestone in diabetes management. Med J Aust 1993; 159: 721-723.
55. Nosadini R, Abaterusso C, Dalla Vestra M et al. Efficacy of antihypertensive therapy in decreasing renal and cardiovascular complications in diabetes mellitus. Nephrol Dial Transplant 1998; 13 Suppl 8: 44-48.
56. Rapaport R, Sills IN. Implications of the DCCT for children and adolescents with IDDM. N J Med 1994; 91:227 -228.
57. (No authors listed). Effect of intensive diabetes management on macrovascular events and risk factors in the Diabetes Control and Complications Trial. Am J Cardiol 1995; 75: 894 -903.
58. Schwartz R, Teramo KA. Pregnancy outcome, Diabetes Control and Complications Trial, and intensive glycemic control. Am J Obstet Gynecol 1998; 178: 416-417.
59. (No authors listed). Pregnancy outcomes in the Diabetes Control and Complications Trial. Am J Obstet Gynecol 1996; 174: 1343-1353.
60. (No authors listed). Effect of intensive therapy on the micro-vascular complications of type 1 diabetes mellitus. Jama 2002; 287: 2563 -2569.
61. (No authors listed). Effects of intensive diabetes therapy on neuropsychological function in adults in the Diabetes Control and Complications Trial. Ann Intern Med 1996; 124: 379 -388.
62. Brink SJ. How to apply the experience from the diabetes con¬trol and complications trial to children and adolescents? Ann Med1997; 29:425-438.
63. (No authors listed). Effect of intensive diabetes treatment on nerve conduction in the Diabetes Control and Complications Trial. Ann Neurol 1995; 38:869-880.
64. Carlisle BA. The implications of diabetes control and complications trial for the pharmacy profession. Ann Pharmac other 1996; 30: 294 -295.
65. Klein R, Moss S. A comparison of the study populations in the Diabetes Control and Complications Trial and the Wisconsin Epidemiologic Study of Diabetic Retinopathy. Arch Intern Med 1995; 155: 745-754.
66. Duron F. Intensive insulin therapy in insulin-dependent diabetes mellitus, the results of the diabetes control and complications trial. Biomed Pharma cother1995; 49: 278 -282.
67. Newman RJ. A method to implement the recommendations of the diabetes control and complications trial in a busy pediatric outpatient practice. Pediatr Ann 1999; 28:594-598.
68. Fenton CL, Clemons PM, Francis GL. How do the results of the diabetes control and complications trial relate to the practice of pediatrics: who should have intensive management? Pediatr Ann 1999; 28: 600-604.
69. Malone JI. Lessons for pediatricians from the diabetes control and complications trial. Pediatr Ann 1994; 23:295-299.
70. Tamborlane WV, Ahern J. Implications and results of the Diabetes Control and Complications Trial. Pediatr Clin North Am 1997; 44: 285-300.
71. Vinik AI, Richardson DW. Implications of the diabetes control and complications trial for persons with non-insulin-dependent diabetes mellitus. South Med J 1997; 90:268 -282.
72. Saudek CD. Non-ophthalmologic findings of the Diabetes Control and Complications Trial. Surv Ophthalmol 1995; 40: 157-162.
73. Nuttall F. Comparison of percent total GHb with percent HbA1c in people with and without known diabetes. Diabetes Care 1998; 21: 1475-1480.
74. Ruggiero L, Glasgow R, Dryfoos JM et al. Diabetes self-management. Self-reported recommendations and patterns in a large population. Diabetes Care 1997; 20:568-576.
75. Levin SR, Coburn JW, Abraira C et al. Effect of intensive glyce¬mic control on microalbuminuria in type 2 diabetes. Veterans Affairs Cooperative Study on Glycemic Control and Complications in Type 2 Diabetes Feasibility Trial Investigators. Diabetes Care 2000; 23: 1478-1485.
76. Rosilio M, Cotton JB, Wieliczko MC et al. Factors associated with glycemic control. A cross-sectional nationwide study in 2,579 French children with type 1 diabetes. The French Pediatric Diabetes Group. Diabetes Care 1998; 21:1146-1153.
77. (No authors listed). Factors influencing glycemic control in young people with type 1 diabetes in Scotland: a population-based study (DIABAUD2). Diabetes Care 2001; 24:239-244.
78. Yokoyama H, Okudaira M, Otani T et al. High incidence of diabetic nephropathy in early-onset Japanese NIDDM patients. Risk analysis. Diabetes Care 1998; 21:1080-1085.
79. Dunn FL, Nathan DM, Scavini M, Selam JL, Wingrove TG. Long-term therapy of IDDM with an implantable insulin pump. The Implantable Insulin Pump Trial Study Group. Diabetes Care 1997; 20:59-63.
80. Miller CD, Phillips LS, Tate MK et al. Meeting American Diabetes Association guidelines in endocrinologist practice. Diabetes Care 2000; 23:444-448.
81. Eastman RC, Javitt JC, Herman WH et al. Model of complications of NIDDM. I. Model construction and assumptions. Diabetes Care 1997; 20:725-734
82. Keen H. The Diabetes Control and Complications Trial (DCCT). Health Trends 1994; 26: 41-43.
83. Tercyak KP Jr., Johnson SB, Kirkpatrick KA, Silverstein JH. Offering a randomized trial of intensive therapy for IDDM to adolescents. Reasons for refusal, patient characteristics, and recruiter effects. Diabetes Care 1998; 21:213-215.
84. Glasgow RE, Ruggiero L, Eakin EG, Dryfoos J, Chobanian L. Quality of life and associated characteristics in a large national sample of adults with diabetes. Diabetes Care 1997; 20:562-567.

Diabetic Retinopathy Study (DRS)
1. (No authors listed). Indications for photocoagulation treatment of diabetic retinopathy: Diabetic Retinopathy Study Report no. 14. The Diabetic Retinopathy Study Research Group. Int Ophthalmol Clin 1987; 27:239-253.
2. Kaufman SC, Ferris FL 3rd, Seigel DG, Davis MD, DeMets DL. Factors associated with visual outcome after photocoagulation for diabetic retinopathy. Diabetic Retinopathy Study Report 13. Invest Ophthalmol Vis Sci 1989; 30:23-28.
3. Ferris FL 3rd, Podgor MJ, Davis MD. Macular edema in Diabetic Retinopathy Study patients. Diabetic Retinopathy Study Report Number 12. Ophthalmology 1987; 94:754-760.
4. Rand LI, Prud'homme GJ, Ederer F, Canner PL. Factors influencing the development of visual loss in advanced diabetic retinopathy. Diabetic Retinopathy Study (DRS) Report No. 10. Invest Ophthalmol Vis Sci 1985; 26:983-991.

Additional Background Reading
1. Kaufman SC, Ferris FL 3rd, Swartz M. Intraocular pressure following panretinal photocoagulation for diabetic retinopathy. Diabetic Retinopathy Report No. 11. Arch Ophthalmol 1987; 105:807-809.
2. Ederer F, Podgor MJ. Assessing possible late treatment effects in stopping a clinical trial early: a case study. Diabetic Retinopathy Study report No. 9. Control Clin Trials 1984; 5:373-381.
3. (No authors listed). Diabetic retinopathy study. Report Number 6. Design, methods, and baseline results. Report Number 7. A modification of the Airlie House classification of diabetic retinopathy. Prepared by the Diabetic Retinopathy. Invest Ophthalmol Vis Sci 1981; 21:1-226.
4. Photocoagulation treatment of proliferative diabetic retinopathy: relationship of adverse treatment effects to retinopathy severity. Diabetic retinopathy study report no. 5. Dev Ophthalmol 1981; 2:248-261.
5. (No authors listed). Photocoagulation treatment of proliferative diabetic retinopathy. Clinical application of Diabetic Retinopathy Study (DRS) findings, DRS Report Number 8. The Diabetic Retinopathy Study Research Group. Ophthalmology 1981; 88:583-600.
6. (No authors listed). Four risk factors for severe visual loss in diabetic retinopathy. The third report from the Diabetic Retinopathy Study. The Diabetic Retinopathy Study Research Group. Arch Ophthalmol 1979; 97:654-655.
7. Preliminary report on effects of photocoagulation therapy. The Diabetic Retinopathy Study Research Group. Am J Ophthalmol 1976; 81: 383-396.

Early Treatment Diabetic Retinopathy Study (ETDRS)
1. Fong DS, Ferris FL 3rd, Davis MD, Chew EY. Causes of severe visual loss in the early treatment diabetic retinopathy study: ETDRS report no. 24. Early Treatment Diabetic Retinopathy Study Research Group. Am J Ophthalmol 1999; 127:137 -141.
2. Chew EY, Klein ML, Murphy RP, Remaley NA, Ferris FL 3rd. Effects of aspirin on vitreous/preretinal hemorrhage in patients with diabetes mellitus. Early Treatment Diabetic Retinopathy Study report no. 20. Arch Ophthalmol 1995; 113: 52-55.
3. (No authors listed). Focal photocoagulation treatment of diabetic macular edema. Relationship of treatment effect to fluorescein angiographic and other retinal characteristics at baseline: ETDRS report no. 19. Early Treatment Diabetic Retinopathy Study Research Group. Arch Ophthalmol 1995; 113: 1144 -1155.
4. (No authors listed). Early photocoagulation for diabetic retinopathy. ETDRS report number 9. Early Treatment Diabetic Retinopathy Study Research Group. Ophthalmology 1991; 98:766-785.
5. (No authors listed). Grading diabetic retinopathy from stereoscopic color fundus photographs -an extension of the modified Airlie House classification. ETDRS report number 10. Early Treatment Diabetic Retinopathy Study Research Group. Ophthalmology 1991; 98:786-806.
6. (No authors listed). Classification of diabetic retinopathy from fluorescein angiograms. ETDRS report number 11. Early Treatment Diabetic Retinopathy Study Research Group. Ophthalmology 1991; 98:807-822.
7. (No authors listed). Fundus photographic risk factors for progression of diabetic retinopathy. ETDRS report number 12. Early Treatment Diabetic Retinopathy Study Research Group. Ophthalmology 1991 May; 98 (5Suppl):823-33.
8. (No authors listed). Treatment techniques and clinical guidelines for photocoagulation of diabetic macular edema. Early Treatment Diabetic Retinopathy Study Report Number 2. Early Treatment Diabetic Retinopathy Study Research Group. Ophthalmology 1987; 94:761-774.
9. (No authors listed). Techniques for scatter and local photocoagulation treatment of diabetic retinopathy: Early Treatment Diabetic Retinopathy Study Report no. 3. The Early Treatment Diabetic Retinopathy Study Research Group. Int Ophthalmol Clin 1987; 27:254-264.
10. Fong DS, Segal PP, Myers F et al. Subretinal fibrosis in diabetic macular edema. ETDRS report 23. Early Treatment Diabetic Retinopathy Study Research Group. Arch Ophthalmol 1997; 115:873-877.

Additional Background Reading
1. Fong DS, Barton FB, Bresnick GH. Impaired color vision associated with diabetic retinopathy: Early Treatment Diabetic Retinopathy Study Report No. 15. Am J Ophthalmol 1999; 128: 612-617.
2. Chew EY, Klein ML, Ferris FL 3rd et al. Association of elevated serum lipid levels with retinal hard exudate in diabetic retinopathy. Early Treatment Diabetic Retinopathy Study (ETDRS) Report 22. Arch Ophthalmol 1996; 114 :1079-1084.
3. Ferris F. Early photocoagulation in patients with either type I or type II diabetes. Trans Am Ophthalmol Soc 1996; 94:505-537.
4. Ferris FL 3rd, Chew EY, Hoogwerf BJ. Serum lipids and diabetic retinopathy. Early Treatment Diabetic Retinopathy Study Research Group. Diabetes Care 1996; 19:1291-1293.
5. Braun CI, Benson WE, Remaley NA, Chew EY, Ferris FL 3rd. Accommodative amplitudes in the Early Treatment Diabetic Retinopathy Study. Retina 1995; 15: 275-281.
6. Prior MJ, Prout T, Miller D, Ewart R, Kumar D. C-peptide and the classification of diabetes mellitus patients in the Early Treatment Diabetic Retinopathy Study. Report number 6. The ETDRS Research Group. Ann Epidemiol 1993; 3:9-17.
7. (No authors listed). Aspirin effects on mortality and morbidity in patients with diabetes mellitus. Early Treatment Dia¬betic Retinopathy Study report 14. ETDRS Investigators. Jama 1992;268:1292-1300.
8. Chew EY, Williams GA, Burton TC et al. Aspirin effects on the development of cataracts in patients with diabetes mellitus. Early treatment diabetic retinopathy study report 16. Arch Ophthalmol 1992;110:339-342.
9. Flynn HW Jr., Chew EY, Simons BD et al. Pars plana vitrectomy in the Early Treatment Diabetic Retinopathy Study. ETDRS report number 17. The Early Treatment Diabetic Retinopathy Study Research Group. Ophthalmology 1992;99:1351-1357.
10. (No authors listed). Early Treatment Diabetic Retinopathy Study design and baseline patient characteristics. ETDRS report number 7. Ophthalmology 1991;98:741-756.
11. (No authors listed). Effects of aspirin treatment on diabetic retinopathy. ETDRS report number 8. Early Treatment Diabetic Retinopathy Study Research Group. Ophthalmology 1991;98:757-765.
12. (No authors listed). Fluorescein angiographic risk factors for progression of diabetic retinopathy. ETDRS report number 13. Early Treatment Diabetic Retinopathy Study Research Group. Ophthalmology 1991;98:834-840.
13. Kinyoun J, Barton F, Fisher M et al. Detection of diabetic macular edema. Ophthalmoscopy versus photography -Early Treatment Diabetic Retinopathy Study Report Number 5. The ETDRS Research Group. Ophthalmology 1989; 96:746 -750; discussion 750-751.
14. (No authors listed). Photocoagulation for diabetic macular edema: Early Treatment Diabetic Retinopathy Study Report no. 4. The Early Treatment Diabetic Retinopathy Study Research Group. Int Ophthalmol Clin 1987;27:265-272.
15. (No authors listed). Photocoagulation for diabetic macular edema. Early Treatment Diabetic Retinopathy Study report number 1. Early Treatment Diabetic Retinopathy Study research group. Arch Ophthalmol 1985;103:1796-1806.
16. Ferris FL 3rd. Photocoagulation for diabetic retinopathy. Early Treatment Diabetic Retinopathy Study Research Group. Jama 1991;266:1263-1265.
17. (No authors listed). Case reports to accompany Early Treatment Diabetic Retinopathy Study Reports 3 and 4. The Early Treatment Diabetic Retinopathy Study Research Group. Int Ophthalmol Clin 1987;27:273-333.
18. (No authors listed). Photocoagulation therapy for diabetic eye disease. Early Treatment Diabetic Retinopathy Study Research Group. Jama 1985;254:3086.


XII. Uveitis and Ocular Inflammation
Epidemiology
1. Jabs DA. Epidemiology of uveitis. Ophthalmic Epidemiol. 2008 Sep-Oct;15(5):283-4.

Evaluation and Grading
1. Bloch-Michel E, Nussenblat RB. International Uveitis Study Group Recommendations for the evaluation of intraocular inflammatory disease. Am J Ophthalmol 1987;103:234-235.
2. Jabs DA, Nussenblatt RB, Rosenbaum JT; Standardization of Uveitis Nomenclature (SUN) Working Group. Standardization of uveitis nomenclature for reporting clinical data. Results of the First International Workshop. Am J Ophthalmol. 2005 Sep;140(3):509-16
3. Tugal-Tutkun I, Herbort CP, Khairallah M, Mantovani A. Interobserver agreement in scoring of dual fluorescein and ICG inflammatory angiographic signs for the grading of posterior segment inflammation. Ocul Immunol Inflamm. 2010 Oct;18(5):385-9.
4. Mahendradas P, Shetty R, Narayana KM, Shetty BK. In vivo confocal microscopy of keratic precipitates in infectious versus noninfectious uveitis. Ophthalmology 2010;117:373-380.
5. Kempen JH, Ganesh SK, Sangwan VS, Rathinam SR. Interobserver agreement in grading activity and site of inflammation in eyes of patients with uveitis. Am J Ophthalmol. 2008 Dec;146(6):813-8.e1.

Approach to Uveitis
1. Herbort CP. Appraisal, work-up and diagnosis of anterior uveitis: a practical approach. Middle East Afr J Ophthalmol. 2009 Oct;16(4):159-67.
2. Agrawal RV, Murthy S, Sangwan V, Biswas J. Current approach in diagnosis and management of anterior uveitis. Indian J Ophthalmol. 2010 Jan-Feb;58(1):11-9.
3. Sudharshan S, Ganesh SK, Biswas J. Current approach in the diagnosis and management of posterior uveitis. Indian J Ophthalmol. 2010 Jan-Feb;58(1):29-43.
4. Bansal R, Gupta V, Gupta A. Current approach in the diagnosis and management of panuveitis. Indian J Ophthalmol. 2010 Jan-Feb;58(1):45-54.
5. Babu BM, Rathinam SR. Intermediate uveitis. Indian J Ophthalmol. 2010 Jan-Feb;58(1):21-7.
6. Mahendradas P, Shetty R, Narayana KM, Shetty BK. In vivo confocal microscopy of keratic precipitates in infectious versus noninfectious uveitis. Ophthalmology 2010;117:373-380.

Scleritis/Episcleritis
1. Jabs DA, Mudun A, Dunn JP, Marsh MJ. Episcleritis and scleritis: clinical features and treatment results. Am J Ophthalmol 2000; 130: 469 -476.

Anterior Uveitis
1. Tay-Kearney ML, Schwam BL, Lowder C et al. Clinical features and associated systemic diseases of HLA-B27 uveitis. Am J Ophthalmol 1996; 121: 47 -56.

Infectious Uveitis
1. Khairallah M, Chee SP, Rathinam SR, Attia S, Nadella V. Novel infectious agents causing uveitis. Int Ophthalmol. 2010 Oct;30(5):465-83.
2. Ur Rehman S, Anand S, Reddy A, Backhouse OC, Mohamed M, Mahomed I, Atkins AD, James T. Poststreptococcal syndrome uveitis: a descriptive case series and literature review. Ophthalmology. 2006 Apr;113(4):701-6.
3. Van Gelder RN. Ocular pathogens for the twenty-first century. Am J Ophthalmol. 2010 Nov;150(5):595-7.
4. Rathinam SR, Ashok KA. Ocular manifestations of systemic disease: ocular parasitosis. Curr Opin Ophthalmol. 2010 Nov;21(6):478-84.
5. Mahendradas P, Ranganna SK, Shetty R et al. Ocular manifestations associated with Chikungunya. Ophthalmology 2008;115:287-291.
6. Dengue-associated maculopathy. Bacsal KE, Chee SP, Cheng CL, Flores JV. Arch Ophthalmol. 2007 Apr; 125(4):501-10

Herpetic Disease
1. Tugal-Tutkun I, Otűk-Yasar B, Altinkurt E. Clinical features and prognosis of herpetic anterior uveitis: a retrospective study of 111 cases. Int Ophthalmol. 2010 Oct;30(5):559-65.
2. Green LK, Pavan-Langston D. Herpes simplex ocular inflammatory disease. Int Ophthalmol Clin. 2006 Spring;46(2):27-37.
3. Herpetic Eye disease Study Group. Acyclovir for the prevention of recurrent herpes simplex virus eye disease. N Engl J Med 1998; 339:300-306.
4. Uchoa UB, Rezende RA, Carrasco MA et al. Long term acyclovir use to prevent recurrent ocular herpes simplex virus infection. Arch Ophthalmol 2003; 121:1702-1704.
5. Chee SP, Bacsal K, Jap A et al. Clinical features of cytomegalovirus anterior uveitis in immunocompetent patients. Am J Ophthalmol 2008;145:834-840.
6. Chee SP, Jap A. Presumed fuchs heterochromic iridocyclitis and Posner-Schlossman syndrome: comparison of cytomegalovirus-positive and negative eyes. Am J Ophthalmol 2008; 146:883-889.
7. Chee SP, Jap A. Cytomegalovirus anterior uveitis: outcome of treatment. Br J Ophthalmol 2010; 94:,1648-1652.

Fuchs Uveitis Syndrome
1. Mohamed Q, Zamir E. Update on Fuchs' uveitis syndrome. Curr Opin Ophthalmol. 2005 Dec;16(6):356-63.
2. Al-Mansour YS, Al-Rajhi AA, Al-Dhibi H, Abu El-Asrar AM. Clinical features and prognostic factors in Fuchs' uveitis. Int Ophthalmol. 2010 Oct;30(5):501-9.
3. Quentin CD, Reiber H. Fuchs heterochromic cyclitis: rubella virus antibodies and genome in aqueous humor. Am J Ophthalmol 2004;138:46-54.
4. Bouchenaki N, Herbort CP. Fluorescein angiographic findings and clinical features in Fuchs' uveitis. Int Ophthalmol 2010;30:511-519.

Cytomegalovirus Retinitis (CMV)
1. Nguyen QD, Kempen JH, Bolton SG, Dunn JP, Jabs DA. Immune recovery uveitis in patients with AIDS and cytomegalovirus retinitis after highly active antiretroviral therapy. Am J Ophthalmol 2000; 129: 634 -639.
2. Robinson MR, Reed G, Csaky KG, Polis MA, Whitcup SM. Immune-recovery uveitis in patients with cytomegalovirus retinitis taking highly active antiretroviral therapy. Am J Ophthalmol 2000; 130: 49 -56.

Toxoplasmosis
1. Dodds EM. Toxoplasmosis. Curr Opin Ophthalmol. 2006 Dec;17(6):557-61.

White Dot Syndromes
1. Quillen DA, Davis JB, Gottlieb JL, Blodi BA, Callanan DG, Chang TS, Equi RA. The white dot syndromes. Am J Ophthalmol. 2004 Mar;137(3):538-50.

Sarcoidosis
1. Herbort CP, Rao NA, Mochizuki M; Member,s of Scientific Committee of First International Workshop on Ocular Sarcoidosis. International criteria for the diagnosis of ocular sarcoidosis: results of the first International Workshop On Ocular Sarcoidosis (IWOS). Ocul Immunol Inflamm. 2009 May-Jun;17(3):160-9.

Tuberculosis
1. Gupta V, Gupta A, Rao NA. Intraocular tuberculosis--an update. Surv Ophthalmol. 2007 Nov-Dec;52(6):561-87.
2. Diagnosis of tuberculous uveitis: clinical application of an interferon-gamma release assay. Ang M, Htoon HM, Chee SP. Ophthalmology. 2009 Jul;116(7):1391-6.

Behçet Disease
1. Kitaichi N, Miyazaki A, Iwata D, Ohno S, Stanford MR, Chams H. Ocular features of Behçet's disease: an international collaborative study. Br J Ophthalmol. 2007 Dec;91(12):1579-82.
2. Hatemi G, Silman A, Bang D, Bodaghi B, Chamberlain AM, Gul A, Houman MH, Kőtter I, Olivieri I, Salvarani C, Sfikakis PP, Siva A, Stanford MR, Stübiger N, Yurdakul S, Yazici H; EULAR Expert Committe. EULAR recommendations for the management of Behçet disease. Ann Rheum Dis. 2008 Dec;67(12):1656-62.
3. Evereklioglu C. Current concepts in the etiology and treatment of Behçet disease. Surv Ophthalmol. 2005 Jul-Aug;50(4):297-350.

Vogt Koyanagi Harada Disease and Sympathetic Ophthalmia
1. Nussenblatt RB. Clinical studies of Vogt-Koyanagi-Harada's disease at the National Eye Institute, NIH, USA. Jpn J Ophthalmol 1988; 32: 330-333.
2. Rao NA, Sukavatcharin S, Tsai JH. Vogt-Koyanagi-Harada disease diagnostic criteria. Int Ophthalmol. 2007 Apr-Jun;27(2-3):195-9.
3. Lertsumitkul S, Whitcup SM, Nussenblatt RB, Chan CC. Sub-retinal fibrosis and choroidal neovascularization in Vogt Koyanagi-Harada syndrome. Graefes Arch Clin Exp Ophthalmol 1999; 237: 1039 -1045.
4. Da Silva FT, Damico FM, Marin ML, Goldberg AC, Hirata CE, Takiuti PH, Olivalves E, Yamamoto JH. Revised diagnostic criteria for vogt-koyanagi-harada disease: considerations on the different disease categories. Am J Ophthalmol. 2009 Feb;147(2):339-345.e5.
5. Chan CC, Roberge RG, Whitcup SM, Nussenblatt RB. 32 cases of sympathetic ophthalmia. A retrospective study at the National Eye Institute, Bethesda, Md., from 1982 to 1992. Arch Ophthalmol 1995; 113: 597-600. [Erratum appears in Arch Ophthalmol 1995; 113: 1507].
6. Galor A, Davis JL, Flynn HW Jr, Feuer WJ, Dubovy SR, Setlur V, Kesen MR, Goldstein DA, Tessler HH, Ganelis IB, Jabs DA, Thorne JE. Sympathetic ophthalmia: incidence of ocular complications and vision loss in the sympathizing eye. Am J Ophthalmol. 2009 Nov;148(5):704-710.e2.

Masquerade Sydromes
1. Rothova A, Ooijman F, Kerkhoff F, Van Der Lelij A, Lokhorst HM. Uveitis masquerade syndromes. Ophthalmology. 2001 Feb;108(2):386-99.

Cystoid Macular Edema
1. Whitcup SM, Csaky KG, Podgor MJ et al. A randomized, masked, cross-over trial of acetazolamide for cystoid macular edema in patients with uveitis. Ophthalmology 1996; 103: 1054 -1062; discussion 1062-1063.
2. Ossewaarde-van Norel A, Rothova A. Clinical review: Update on treatment of inflammatory macular edema. Ocul Immunol Inflamm. 2011 Feb;19(1):75-83.

Immunosuppression
1. Jabs DA, Rosenbaum JT, Foster CS et al. Guidelines for the use of immunosuppressive drugs in patients with ocular inflammatory disorders: recommendations of an expert panel. Am J Ophthalmol 2000; 130: 492 -513.
2. Lobo AM, Sobrin L, Papaliodis GN. Drug delivery options for the treatment of ocular inflammation. Semin Ophthalmol. 2010 Sep-Nov;25(5-6):283-8.
3. Lee SS, Hughes PM, Robinson MR. Recent advances in drug delivery systems for treating ocular complications of systemic diseases. Curr Opin Ophthalmol. 2009 Nov;20(6):511-9.
4. Jap A, Chee SP. Immunosuppressive therapy for ocular diseases. Curr Opin Ophthalmol. 2008 Nov;19(6):535-40.
5. Sugita S. Intravitreal anti-inflammatory treatment for uveitis. Br J Ophthalmol. 2007 Feb;91(2):135-6.
6. Imrie FR, Dick AD. Biologics in the treatment of uveitis. Curr Opin Ophthalmol 2007;18:481-486.
7. Sfikakis PP, Markomichelakis N, Alpsoy E et al. Anti-TNF therapy in the management of BehVet’s disease –review and basis for recommendations. Rheumatology 2007;46:736-741.
8. Kempen JH, Daniel E, Gangaputra S et al. Methods for identifying long-term adverse effects of treatment in patients with eye diseases: the Systemic Immunosuppressive Therapy for Eye Diseases (SITE) Cohort Study. Ophthalmic Epidemiol 2008;15:47-55.

Investigations and Imaging
1. Singh RP, Young LH. Diagnostic tests for posterior segment inflammation. Int Ophthalmol Clin. 2006 Spring;46(2):195-208.
2. Herbort CP. Fluorescein and indocyanine green angiography for uveitis. Middle East Afr J Ophthalmol. 2009 Oct;16(4):168-87.
3. Gallagher MJ, Yilmaz T, Cervantes-Castañeda RA, Foster CS. The characteristic features of optical coherence tomography in posterior uveitis. Br J Ophthalmol. 2007 Dec;91(12):1680-5.


XIII. Ocular Oncology
This list is not exhaustive and the reading material is recommended and not required.

Textbooks
1. Damato B, Groenewald C. Surgery for intraocular tumors. In: Bhavsar AR, editor. Retina and vitreous surgery. Philadelphia: Elsevier; 2009. p. 229-44.
2. Damato B. Ocular tumors: Diagnosis and Treatment. Oxford: Butterworth Heinemann; 2000.
3. Jager MJ, Desjardins L, Kivela T, Damato BE. Current Concepts in Uveal
Melanoma. In: Bandello F, editor. Developments in Ophthalmology. Vol 49.
Basel. Karger; 2012
4. Kanski JJ, Milewski SA, Damato BE, Tanner V. Tumors. Diseases of the ocular fundus. Edinburgh: Elsevier Mosby; 2005. p. 281-325.
5. Ocular oncology. New York: Marcel Dekker; 2003.
6. Ophthalmic oncology. Philadelphia: Saunders; 2005.
7. Ophthalmic pathology and intraocular tumors. San Francisco: American Academy of Ophthalmology; 2009.
8. Shields JA, Shields CL. Eyelid, conjunctival and orbital tumors. An atlas and textbook. Second ed. Philadelphia: Lippincott Williams & Wilkins; 2008.
9. Shields JA, Shields CL. Intraocular tumors. An atlas and textbook. Second Edition ed. Philadelphia: Lippincott Williams & Wilkins; 2008.
10. Singh AD, Damato BE, Pe'er J, Murphree AL, Perry JD. Clinical Ophthalmic Oncology. London: Elsevier; 2006.
11. Therapeutic approaches to ocular tumors. In: Spaeth GL, editor. Ophthalmic Surgery.Philadelphia: Saunders; 2003. p. 699-734.
12. TNM staging of malignant tumors (7th ed). 7th ed. New York/Berlin: Springer; 2009.
13. Tumors of the retina, choroid, and vitreous. In: Schachat AP, editor. Retina. 4th ed. Philadelphia: Mosby; 2006. p. 557-872.
14. Tumors. Philadelphia: Lippincott Williams & Wilkins; 2008.
15. Uveal melanoma: a model for exploring fundamental cancer biology. London: Taylor & Francis; 2004.
16. Zografos L. Tumeurs intraoculaires. Paris: Masson; 2002.

Uveal Melanoma
1. All-Ericsson C, Girnita L, Seregard S, Bartolazzi A, Jager MJ, Larsson O. Insulin-like growth factor-1 receptor in uveal melanoma: a predictor for metastatic disease and a potential therapeutic target. Invest Ophthalmol Vis Sci 2002 January;43(1):1-8.
2. Barak V, Kaiserman I, Frenkel S, Hendler K, Kalickman I, Pe'er J. The dynamics of serum tumor markers in predicting metastatic uveal melanoma (part 1). Anticancer Res 2011 January;31(1):345-9.
3. Bauer J, Kilic E, Vaarwater J, Bastian BC, Garbe C, de KA. Oncogenic GNAQ mutations are not correlated with disease-free survival in uveal melanoma. Br J Cancer 2009 September 1;101(5):813-5.
4. Bechrakis NE, Hocht S, Martus P, Kreusel KM, Heese J, Foerster MH. [Endoresection following proton beam irradiation of large uveal melanomas]. Ophthalmologe 2004 April;101(4):370-6.
5. Bechrakis NE, Petousis VE, Willerding G et al. Ten year results of transscleral resection of large uveal melanomas:Local tumor control and metastatic rate. Br J Ophthalmol 2009 December 3.
6. Bechrakis NE, Sehu KW, Lee WR, Damato BE, Foerster MH. Transformation of cell type in uveal melanomas: a quantitative histologic analysis. Arch Ophthalmol 2000 October;118(10):1406-12.
7. Bedikian AY, Johnson MM, Warneke CL et al. Systemic therapy for unresectable metastatic melanoma: impact of biochemotherapy on long-term survival. J Immunotoxicol 2008 April;5(2):201-7.
8. Bergman L, Seregard S, Nilsson B, Lundell G, Ringborg U, Ragnarsson-Olding B. Uveal melanoma survival in Sweden from 1960 to 1998. Invest Ophthalmol Vis Sci 2003 August;44(8):3282-7.
9. Chang SH, Worley LA, Onken MD, Harbour JW. Prognostic biomarkers in uveal melanoma: evidence for a stem cell-like phenotype associated with metastasis. Melanoma Res 2008 June;18(3):191-200.
10. Char DH, Kroll S, Phillips TL, Quivey JM. Late radiation failures after iodine 125 brachytherapy for uveal melanoma compared with charged-particle (proton or helium ion) therapy. Ophthalmology 2002 Oct;109(10):1850-4.
11. Char DH, Miller T, Crawford JB. Eye-wall resection. Trans Am Ophthalmol Soc 2000;98:153-9; discussion 159-61.:153-9.
12. Char DH, Miller T, Crawford JB. Uveal tumor resection. Br J Ophthalmol 2001 October;85(10):1213-9.
13. Conway RM, Poothullil AM, Daftari IK, Weinberg V, Chung JE, O'Brien JM. Estimates of ocular and visual retention following treatment of extra-large uveal melanomas by proton beam radiotherapy. Arch Ophthalmol 2006 Jun;124(6):838-43.
14. Cook SA, Damato B, Marshall E, Salmon P. Psychological aspects of cytogenetic testing of uveal melanoma: preliminary findings and directions for future research. Eye (Lond) 2009 March;23(3):581-5.
15. Cook SA, Damato B, Marshall E, Salmon P. Psychological aspects of cytogenetic testing of uveal melanoma: preliminary findings and directions for future research. Eye 2008 March 14.
16. Cook SA, Damato B, Marshall E, Salmon P. Reconciling the principle of patient autonomy with the practice of informed consent: decision-making about prognostication in uveal melanoma. Health Expect 2010 October 28;10-7625.
17. Coupland SE, Campbell I, Damato B. Routes of Extraocular Extension of Uveal Melanoma Risk Factors and Influence on Survival Probability. Ophthalmology 2008 June 11.
18. Damato B, Coupland SE. A reappraisal of the significance of largest basal diameter of posterior uveal melanoma. Eye (Lond) 2009 December;23(12):2152-60.
19. Damato B, Dopierala JA, Coupland SE. Genotypic profiling of 452 choroidal melanomas with multiplex ligation-dependent probe amplification. Clin Cancer Res 2010 December 15;16(24):6083-92.
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25. Damato B, Kacperek A, Chopra M, Sheen MA, Campbell IR, Errington RD. Proton beam radiotherapy of iris melanoma. Int J Radiat Oncol Biol Phys 2005 Sep 1;63(1):109-15.
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41. Ferreyra HA, Goldbaum MH, Weinreb RN. Endoresection of irradiated choroidal melanoma as a treatment for intractable vitreous hemorrhage and secondary blood-induced glaucoma. Semin Ophthalmol 2008 March;23(2):135-8.
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44. Garcia-Arumi J, Balaguer O, Fonollosa A, Boixadera A, Martinez-Castillo VJ. Endoresection in high posterior choroidal melanomas: long-term outcome. British Journal of Ophthalmology. In press 2008.
45. Gragoudas ES, Lane AM, Munzenrider J, Egan KM, Li W. Long-term risk of local failure after proton therapy for choroidal/ciliary body melanoma. Trans Am Ophthalmol Soc 2002;100:43-8; discussion 48-9.:43-8.
46. Gragoudas ES. Proton beam irradiation of uveal melanomas: the first 30 years. The Weisenfeld Lecture. Invest Ophthalmol Vis Sci 2006 Nov;47(11):4666-73.
47. Gupta S, Bedikian AY, Ahrar J et al. Hepatic artery chemoembolization in patients with ocular melanoma metastatic to the liver: response, survival, and prognostic factors. Am J Clin Oncol 2010 October;33(5):474-80.
48. Hadden PW, Hiscott PS, Damato BE. Histopathology of eyes enucleated after endoresection of choroidal melanoma. Ophthalmology 2004 January;111(1):154-60.
49. Harbour JW. Molecular prognostic testing and individualized patient care in uveal melanoma. Am J Ophthalmol 2009 December;148(6):823-9.
50. Hawkins BS. The Collaborative Ocular Melanoma Study (COMS) randomized trial of pre-enucleation radiation of large choroidal melanoma: IV. Ten-year mortality findings and prognostic factors. COMS report number 24. Am J Ophthalmol 2004 December;138(6):936-51.
51. Huppert PE, Fierlbeck G, Pereira P et al. Transarterial chemoembolization of liver metastases in patients with uveal melanoma. Eur J Radiol 2009 May.
52. Isager P, Engholm G, Overgaard J, Storm H. Uveal and conjunctival malignant melanoma in denmark 1943-97: observed and relative survival of patients followed through 2002. Ophthalmic Epidemiol 2006 April;13(2):85-96.
53. Karkhaneh R, Chams H, Amoli FA et al. Long-term surgical outcome of posterior choroidal melanoma treated by endoresection. Retina 2007 September;27(7):908-14.
54. Kennedy AS, Nutting C, Jakobs T et al. A first report of radioembolization for hepatic metastases from ocular melanoma. Cancer Invest 2009 July;27(6):682-90.
55. Kim IK, Lane AM, Egan KM, Munzenrider J, Gragoudas ES. Natural history of radiation papillopathy after proton beam irradiation of parapapillary melanoma. Ophthalmology 2010 Aug;117(8):1617-22.
56. Kim JW, Damato BE, Hiscott P. Noncontiguous tumor recurrence of posterior uveal melanoma after transscleral local resection. Arch Ophthalmol 2002 December;120(12):1659-64.
57. Kujala E, Makitie T, Kivela T. Very long-term prognosis of patients with malignant uveal melanoma. Invest Ophthalmol Vis Sci 2003 November;44(11):4651-9.
58. Lake SL, Coupland SE, Taktak AF, Damato BE. Whole genome microarray detects deletions and loss of heterozygosity of chromosome 3 occurring exclusively in metastasizing uveal melanoma. Invest Ophthalmol Vis Sci 2010 May 5.
59. Lane AM, Egan KM, Harmon D, Holbrook A, Munzenrider JE, Gragoudas ES. Adjuvant Interferon Therapy for Patients with Uveal Melanoma at High Risk of Metastasis. Ophthalmology 2009 November;116(11):2206-12.
60. Lane AM, Egan KM, Kim IK, Gragoudas ES. Mortality after diagnosis of small melanocytic lesions of the choroid. Arch Ophthalmol 2010 August;128(8):996-1000.
61. Langmann G, Pendl G, Klaus-Mulln e, Papaefthymiou G, Guss H. Gamma knife radiosurgery for uveal melanomas: an 8-year experience. J Neurosurg 2000 December;93 Suppl 3:184-8:184-8.
62. Langmann G, Pendl G, Mullner K, Feichtinger KH, Papaefthymiouaf G. High-compared with low-dose radiosurgery for uveal melanomas. J Neurosurg 2002 December;97(5 Suppl):640-3.
63. Lumbroso-Le Rouic L, Delacroix S, Dendale R, Levy-Gabriel C, Feuvret L, Noel G, et al. Proton beam therapy for iris melanomas. Eye 2006 Nov;20(11):1300-5.
64. Maat W, Haasnoot GW, Claas FH, Schalij-Delfos NE, Schreuder GM, Jager MJ. HLA Class I and II genotype in uveal melanoma: relation to occurrence and prognosis. Invest Ophthalmol Vis Sci 2006 January;47(1):3-6.
65. Maat W, Jordanova ES, van Zelderen-Bhola SL et al. The heterogeneous distribution of monosomy 3 in uveal melanomas: implications for prognostication based on fine-needle aspiration biopsies. Arch Pathol Lab Med 2007 January;131(1):91-6.
66. Maat W, Ly LV, Jordanova ES, de Wolff-Rouendaal D, Schalij-Delfos NE, Jager MJ. Monosomy of chromosome 3 and an inflammatory phenotype occur together in uveal melanoma. Invest Ophthalmol Vis Sci 2008 February;49(2):505-10.
67. Mariani P, Piperno-Neumann S, Servois V et al. Surgical management of liver metastases from uveal melanoma: 16 years' experience at the Institut Curie. Eur J Surg Oncol 2009 November;35(11):1192-7.
68. Marucci L, Ancukiewicz M, Lane AM, Collier JM, Gragoudas ES, Munzenrider JE. Uveal melanoma recurrence after fractionated proton beam therapy: comparison of survival in patients treated with reirradiation or with enucleation. Int J Radiat Oncol Biol Phys 2011 Mar 1;79(3):842-6.
69. Marucci L, Ancukiewicz M, Lane AM, Collier JM, Gragoudas ES, Munzenrider JE. Uveal melanoma recurrence after fractionated proton beam therapy: comparison of survival in patients treated with reirradiation or with enucleation. Int J Radiat Oncol Biol Phys 2011 March 1;79(3):842-6.
70. Mashayekhi A, Shields CL, Lee SC, Marr BP, Shields JA. Retinal break and rhegmatogenous retinal detachment after transpupillary thermotherapy as primary or adjunct treatment of choroidal melanoma. Retina 2008 February;28(2):274-81.
71. Mensink HW, Vaarwater J, de Keizer RJ et al. Chromosomal aberrations in iris melanomas. Br J Ophthalmol 2011 March;95(3):424-8.
72. Mensink HW, Vaarwater J, Kilic E et al. Chromosome 3 intratumor heterogeneity in uveal melanoma. Invest Ophthalmol Vis Sci 2009 February;50(2):500-4.
73. Mittica N, Vemuganti GK, Duffy M, Torczynski E, Edward DP. Late orbital recurrence of a choroidal melanoma following internal resection: report of a case and review of the literature. Surv Ophthalmol 2003 March;48(2):181-90.
74. Modorati G, Miserocchi E, Galli L, Picozzi P, Rama P. Gamma knife radiosurgery for uveal melanoma: 12 years of experience. Br J Ophthalmol 2009 January;93(1):40-4.
75. Mueller AJ, Talies S, Schaller UC, Horstmann G, Wowra B, Kampik A. Stereotactic radiosurgery of large uveal melanomas with the gamma-knife. Ophthalmology 2000 July;107(7):1381-7.
76. Murthy R, Honavar SG, Naik M, Reddy VA, Vemuganti GK. Clinicopathologic findings in choroidal melanomas after failed transpupillary thermotherapy. Am J Ophthalmol 2004 March;137(3):594-5.
77. Parrozzani R, Boccassini B, de B, V, Radin PP, Midena E. Long-term outcome of transpupillary thermotherapy as primary treatment of selected choroidal melanoma. Acta Ophthalmol 2009 November;87(7):789-92.
78. Rivoire M, Kodjikian L, Negrier S. Prolonged survival after complete resection of metastases from intraocular melanoma. Cancer 2004 July 1;101(1):207-8.
79. Rundle P, Singh AD, Rennie I. Proton beam therapy for iris melanoma: a review of 15 cases. Eye 2007 Jan;21(1):79-82.
80. Schilling H, Bornfeld N, Talies S et al. [Endoresection of large uveal melanomas after pretreatment by single-dose stereotactic convergence irradiation with the leksell gamma knife--first experience on 46 cases]. Klin Monatsbl Augenheilkd 2006 June;223(6):513-20.
81. Servois V, Mariani P, Malhaire C et al. Preoperative staging of liver metastases from uveal melanoma by magnetic resonance imaging (MRI) and fluorodeoxyglucose-positron emission tomography (FDG-PET). Eur J Surg Oncol 2010 February;36(2):189-94.
82. Shields CL, Ganguly A, Bianciotto CG, Turaka K, Tavallali A, Shields JA. Prognosis of uveal melanoma in 500 cases using genetic testing of fine-needle aspiration biopsy specimens. Ophthalmology 2011 February;118(2):396-401.
83. Shields CL, Shields JA, Perez N, Singh AD, Cater J. Primary transpupillary thermotherapy for small choroidal melanoma in 256 consecutive cases: outcomes and limitations. Ophthalmology 2002 February;109(2):225-34.
84. Singh AD, Eagle RC, Jr., Shields CL, Shields JA. Clinicopathologic reports, case reports, and small case series: enucleation following transpupillary thermotherapy of choroidal melanoma: clinicopathologic correlations. Arch Ophthalmol 2003 March;121(3):397-400.
85. Singh AD, Rennie IG, Kivela T, Seregard S, Grossniklaus H. The Zimmerman-McLean-Foster hypothesis: 25 years later. Br J Ophthalmol 2004 July;88(7):962-7.
86. Singh AD, Rundle PA, Berry-Brincat A, Parsons MA, Rennie IG. Extrascleral extension of choroidal malignant melanoma following transpupillary thermotherapy. Eye 2004 January;18(1):91-3.
87. Starr OD, Patel DV, Allen JP, McGhee CN. Iris melanoma: pathology, prognosis and surgical intervention. Clin Experiment Ophthalmol 2004 June;32(3):294-6.
88. Straatsma BR, Diener-West M, Caldwell R, Engstrom RE. Mortality after deferral of treatment or no treatment for choroidal melanoma. Am J Ophthalmol 2003 July;136(1):47-54.
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90. Toivonen P, Makitie T, Kujala E, Kivela T. Microcirculation and tumor-infiltrating macrophages in choroidal and ciliary body melanoma and corresponding metastases. Invest Ophthalmol Vis Sci 2004 January;45(1):1-6.
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93. Tsai T, O'Brien JM, Engstrom R, Straatsma BR. Extrascleral extension of a choroidal melanoma after argon photocoagulation and transpupillary thermotherapy. Br J Ophthalmol 2002 March;86(3):358-9.
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Retinoblastoma
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2. Abouzeid H, Schorderet DF, Balmer A, Munier FL. Germline mutations in retinoma patients: relevance to low-penetrance and low-expressivity molecular basis. Mol Vis 2009;15:771-7. Epub;%2009 Apr 17.:771-7.
3. Ali MJ, Reddy VA, Honavar SG, Naik M. Orbital retinoblastoma: Where do we go from here? J Cancer Res Ther 2011 January;7(1):11-4.
4. Brisse HJ, Guesmi M, Aerts I et al. Relevance of CT and MRI in retinoblastoma for the diagnosis of postlaminar invasion with normal-size optic nerve: a retrospective study of 150 patients with histological comparison. Pediatr Radiol 2007 July;37(7):649-56.
5. Bunin GR, Felice MA, Davidson W et al. Medical radiation exposure and risk of retinoblastoma resulting from new germline RB1 mutation. Int J Cancer 2011 May 1;128(10):2393-404.
6. Chantada, G., F. Doz, et al. (2006). "A proposal for an international retinoblastoma staging system." Pediatr Blood Cancer 47(6): 801-805.
7. de Graaf, P., S. Goricke, et al. (2011). "Guidelines for imaging retinoblastoma: imaging principles and MRI standardization." Pediatr Radiol.Dunkel IJ, Chan HS, Jubran R et al. High-dose chemotherapy with autologous hematopoietic stem cell rescue for stage 4B retinoblastoma. Pediatr Blood Cancer 2010 July 15;55(1):149-52.
8. Dunkel IJ, Jubran RF, Gururangan S et al. Trilateral retinoblastoma: potentially curable with intensive chemotherapy. Pediatr Blood Cancer 2010 March;54(3):384-7.
9. Kivela T. Trilateral retinoblastoma: a meta-analysis of hereditary retinoblastoma associated with primary ectopic intracranial retinoblastoma. J Clin Oncol 1999 June;17(6):1829-37.
10. Kivela T. 200 years of success initiated by James Wardrop's 1809 monograph on retinoblastoma. Acta Ophthalmol 2009 November;87(8):810-2.
11. Kleinerman RA, Tucker MA, Abramson DH, Seddon JM, Tarone RE, Fraumeni JF, Jr. Risk of soft tissue sarcomas by individual subtype in survivors of hereditary retinoblastoma. J Natl Cancer Inst 2007 January 3;99(1):24-31.
12. Knudson AG. Two genetic hits (more or less) to cancer. Nat Rev Cancer 2001 November;1(2):157-62.
13. Levy J, Frenkel S, Baras M, Neufeld M, Pe'er J. Calcification in retinoblastoma: histopathologic findings and statistical analysis of 302 cases. Br J Ophthalmol 2011 January 27.
14. Lin P, O'Brien JM. Frontiers in the management of retinoblastoma. Am J Ophthalmol 2009 August;148(2):192-8.
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17. Lohmann DR, Gallie BL, Gobin YP et al. Retinoblastoma
18. Lumbroso-Le RL, Aerts I, Levy-Gabriel C et al. Conservative treatments of intraocular retinoblastoma. Ophthalmology 2008 August;115(8):1405-10, 1410.
19. Munier FL, Verwey J, Pica A et al. New developments in external beam radiotherapy for retinoblastoma: from lens to normal tissue-sparing techniques. Clin Experiment Ophthalmol 2008 January;36(1):78-89.
20. Osman IM, Abouzeid H, Balmer A et al. Modern cataract surgery for radiation-induced cataracts in retinoblastoma. Br J Ophthalmol 2011 February;95(2):227-30.
21. Pogrzebielski A, Shields CL, Romanowska-Dixon B, Shields JA. [Retinoblastoma update--management and classification (Part I)]. Klin Oczna 2006;108(4-6):253-7.
22. Pogrzebielski A, Shields CL, Romanowska-Dixon B, Shields JA. [Retinoblastoma update--therapy (Part II)]. Klin Oczna 2006;108(4-6):258-62.
23. Rodriguez-Galindo C, Wilson MW, Chantada G et al. Retinoblastoma: one world, one vision. Pediatrics 2008 September;122(3):e763-e770.
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25. Schefler AC, Abramson DH. Retinoblastoma: what is new in 2007-2008. Curr Opin Ophthalmol 2008 November;19(6):526-34.
26. Shields CL, Ghassemi F, Tuncer S, Thangappan A, Shields JA. Clinical spectrum of diffuse infiltrating retinoblastoma in 34 consecutive eyes. Ophthalmology 2008 December;115(12):2253-8.
27. Shields CL, Shields JA. Retinoblastoma management: advances in enucleation, intravenous chemoreduction, and intra-arterial chemotherapy. Curr Opin Ophthalmol 2010 May;21(3):203-12.
28. Shields CL, Shields JA. Basic understanding of current classification and management of retinoblastoma. Curr Opin Ophthalmol 2006 June;17(3):228-34.
29. Vahedi A, Lumbroso-Le RL, Levy GC et al. [Differential diagnosis of retinoblastoma: a retrospective study of 486 cases]. J Fr Ophtalmol 2008 February;31(2):165-72.
30. Zage PE, Reitman AJ, Seshadri R et al. Outcomes of a two-drug chemotherapy regimen for intraocular retinoblastoma. Pediatr Blood Cancer 2008 March;50(3):567-72.

Other Intraocular Tumors
1. Aizman A, Finger PT, Shabto U, Szechter A, Berson A. Palladium 103 (103Pd) plaque radiation therapy for circumscribed choroidal hemangioma with retinal detachment. Arch Ophthalmol 2004 November;122(11):1652-6.
2. Ascaso FJ, Villen L. Fundus Autofluorescence Imaging Findings in Choroidal Osteoma. Retina 2011 April 9.
3. Augsburger JJ, Henson GL, Hershberger VS, Trichopoulos N. Topographical distribution of typical unifocal congenital hypertrophy of retinal pigment epithelium. Graefes Arch Clin Exp Ophthalmol 2006 November;244(11):1412-4.
4. Bianciotto C, Shields CL, Lally SE, Freire J, Shields JA. CyberKnife radiosurgery for the treatment of intraocular and periocular lymphoma. Arch Ophthalmol 2010 December;128(12):1561-7.
5. Cassoux N, Giron A, Bodaghi B et al. IL-10 measurement in aqueous humor for screening patients with suspicion of primary intraocular lymphoma. Invest Ophthalmol Vis Sci 2007 July;48(7):3253-9.
6. Chan CC, Fisson S, Bodaghi B. The future of primary intraocular lymphoma (retinal lymphoma). Ocul Immunol Inflamm 2009 November;17(6):375-9.
7. Chan JW. Paraneoplastic retinopathies and optic neuropathies. Surv Ophthalmol 2003 January;48(1):12-38.
8. Chan RP, Lai TY. Photodynamic therapy with verteporfin for vasoproliferative tumor of the retina. Acta Ophthalmol 2010 September;88(6):711-2.
9. Chan RV, Yonekawa Y, Lane AM et al. Proton beam irradiation using a light-field technique for the treatment of choroidal hemangiomas. Ophthalmologica 2010;224(4):209-16.
10. Chen J, Lee L, Gass JD. Choroidal osteoma: evidence of progression and decalcification over 20 years. Clin Exp Optom 2006 March;89(2):90-4.
11. Cohen VM, Shields CL, Demirci H, Shields JA. Iodine I 125 plaque radiotherapy for vasoproliferative tumors of the retina in 30 eyes. Arch Ophthalmol 2008 September;126(9):1245-51.
12. Coupland SE, Chan CC, Smith J. Pathophysiology of retinal lymphoma. Ocul Immunol Inflamm 2009 July;17(4):227-37.
13. Coupland SE, Damato B. Lymphomas involving the eye and the ocular adnexa. Curr Opin Ophthalmol 2006 December;17(6):523-31.
14. Coupland SE, Damato B. Understanding intraocular lymphomas. Clin Experiment Ophthalmol 2008 August;36(6):564-78.
15. Coupland SE, Hummel M, Muller HH, Stein H. Molecular analysis of immunoglobulin genes in primary intraocular lymphoma. Invest Ophthalmol Vis Sci 2005 October;46(10):3507-14.
16. Damato B. Vasoproliferative retinal tumor. Br J Ophthalmol 2006 April;90(4):399-400.
17. De SG, Krebs I, Binder S. High-definition optical coherence tomography in a case of congenital hypertrophy of the retinal pigment epithelium. Ophthalmic Surg Lasers Imaging 2010 November;41 Suppl:S93-5. doi: 10.3928/15428877-20101031-04.:S93-S95.
18. Demirci H, Shields CL, Chao AN, Shields JA. Uveal metastasis from breast cancer in 264 patients. Am J Ophthalmol 2003 August;136(2):264-71.
19. Eagle RC, Jr., Shields JA, Shields CL, Wood MG. Hamartomas of the iris and ciliary epithelium in tuberous sclerosis complex. Arch Ophthalmol 2000 May;118(5):711-5.
20. Esmaili DD, Mukai S, Jakobiec FA, Kim IK, Gragoudas ES. Ocular melanocytoma. Int Ophthalmol Clin 2009;49(1):165-75.
21. Frenkel S, Hendler K, Siegal T, Shalom E, Pe'er J. Intravitreal methotrexate for treating vitreoretinal lymphoma: 10 years of experience. Br J Ophthalmol 2008 March;92(3):383-8.
22. Galiatsatos P, Foulkes WD. Familial adenomatous polyposis. Am J Gastroenterol 2006 February;101(2):385-98.
23. Goldberg S, Frenkel S, Blumenthal EZ, Solomon A, Pe'er J. Intraocular lymphoma. Ophthalmology 2007 June;114(6):1236-7.
24. Grant LW, Anderson C, Macklis RM, Singh AD. Low dose irradiation for diffuse choroidal hemangioma. Ophthalmic Genet 2008 December;29(4):186-8.
25. Grenga PL, Sagoo MS, Malagola R. Recurrent vitreous haemorrhage from sporadic retinal astrocytic hamartoma. Eye (Lond) 2007 May;21(5):682-4.
26. Grimm SA, McCannel CA, Omuro AM et al. Primary CNS lymphoma with intraocular involvement: International PCNSL Collaborative Group Report. Neurology 2008 October 21;71(17):1355-60.
27. Grimm SA, Pulido JS, Jahnke K et al. Primary intraocular lymphoma: an International Primary Central Nervous System Lymphoma Collaborative Group Report. Ann Oncol 2007 November;18(11):1851-5.
28. Heimann H, Damato B. Congenital vascular malformations of the retina and choroid. Eye (Lond) 2010 March;24(3):459-67.
29. Itty S, Pulido JS. Rituximab for intraocular lymphoma. Retina 2009 February;29(2):129-32.
30. Jahnke K, Korfel A, Komm J et al. Intraocular lymphoma 2000-2005: results of a retrospective multicentre trial. Graefes Arch Clin Exp Ophthalmol 2006 June;244(6):663-9.
31. Karp CL, Galor A, Chhabra S, Barnes SD, Alfonso EC. Subconjunctival/perilesional recombinant interferon alpha2b for ocular surface squamous neoplasia: a 10-year review. Ophthalmology 2010 December;117(12):2241-6.
32. Kenawy N, Groenwald C, Damato B. Treatment of a vasoproliferative tumor with intravitreal bevacizumab (Avastin). Eye (Lond) 2007 June;21(6):893-4.
33. Kitzmann AS, Pulido JS, Ferber MJ, Highsmith WE, Babovic-Vuksanovic D. A splice-site mutation in CCM1/KRIT1 is associated with retinal and cerebral cavernous hemangioma. Ophthalmic Genet 2006 December;27(4):157-9.
34. Kitzmann AS, Pulido JS, Mohney BG et al. Intraocular use of rituximab. Eye (Lond) 2007 December;21(12):1524-7.
35. Kong DS, Lee JI, Kang SW. Gamma knife radiosurgery for choroidal hemangioma. Am J Ophthalmol 2007 August;144(2):319-22.
36. Krohn J, Froystein T, Dahl O. Topography of solitary congenital hypertrophy of the retinal pigment epithelium in the ocular fundus. Acta Ophthalmol 2009 November;87(8):921-2.
37. Kwan AS, Ramkissoon YD, Gregor ZJ. Surgical management of retinal capillary hemangioblastoma associated with retinal detachment. Retina 2008 October;28(8):1159-62.
38. Labauge P, Krivosic V, Denier C, Tournier-Lasserve E, Gaudric A. Frequency of retinal cavernomas in 60 patients with familial cerebral cavernomas: a clinical and genetic study. Arch Ophthalmol 2006 June;124(6):885-6.
39. Lazzeri S, Figus M, Di BE, Rizzo S, Nardi M. Verteporfin photodynamic therapy for retinal hemangioblastoma associated with Von Hippel-Lindau disease in a 9-year-old child. Clin Experiment Ophthalmol 2011 March;39(2):179-81.
40. Lee BJ, Lowder CY, Biscotti C, Schoenfield L, Singh AD. Ciliary body metastasis masquerading as scleritis. Br J Ophthalmol 2007 December;91(12):1582, 1649.
41. Levy-Gabriel C, Rouic LL, Plancher C et al. Long-term results of low-dose proton beam therapy for circumscribed choroidal hemangiomas. Retina 2009 February;29(2):170-5.
42. Leys AM, Silva R, Inhoffen W, Tatar O. Neovascular growth following photodynamic therapy for choroidal hemangioma and neovascular regression after intravitreous injection of triamcinolone. Retina 2006 July;26(6):693-7.
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44. Lu Y, Jia L, He S et al. Melanoma-associated retinopathy: a paraneoplastic autoimmune complication. Arch Ophthalmol 2009 December;127(12):1572-80.
45. Meunier J, Lumbroso-Le RL, Vincent-Salomon A et al. Ophthalmologic and intraocular non-Hodgkin's lymphoma: a large single centre study of initial characteristics, natural history, and prognostic factors. Hematol Oncol 2004 December;22(4):143-58.
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48. Parsons MA, Rennie IG, Rundle PA, Dhingra S, Mudhar H, Singh AD. Congenital hypertrophy of retinal pigment epithelium: a clinico-pathological case report. Br J Ophthalmol 2005 July;89(7):920-1.
49. Patikulsila D, Visaetsilpanonta S, Sinclair SH, Shields JA. Cavernous hemangioma of the optic disk. Retina 2007 March;27(3):391-2.
50. Pe'er J, Hochberg FH, Foster CS. Clinical review: treatment of vitreoretinal lymphoma. Ocul Immunol Inflamm 2009 September;17(5):299-306.
51. Powell SF, Dudek AZ. Treatment of melanoma-associated retinopathy. Curr Treat Options Neurol 2010 January;12(1):54-63.
52. Rajagopal R, Harbour JW. Diagnostic testing and treatment choices in primary vitreoretinal lymphoma. Retina 2011 March;31(3):435-40.
53. Ramaesh K, Marshall JW, Wharton SB, Dhillon B. Intraocular metastases of cutaneous malignant melanoma: a case report and review of the literature. Eye (Lond) 1999 April;13(Pt 2):247-50.
54. Ramasubramanian A, Shields CL, Harmon SA, Shields JA. Autofluorescence of choroidal hemangioma in 34 consecutive eyes. Retina 2010 January;30(1):16-22.
55. Raparia K, Chang CC, Chevez-Barrios P. Intraocular lymphoma: diagnostic approach and immunophenotypic findings in vitrectomy specimens. Arch Pathol Lab Med 2009 August;133(8):1233-7.
56. Rennie IG. Retinal vasoproliferative tumors. Eye (Lond) 2010 March;24(3):468-71.
57. Saldanha MJ, Edrich C. Treatment of vasoproliferative tumors with photodynamic therapy. Ophthalmic Surg Lasers Imaging 2008 March;39(2):143-5.
58. Sasmal NK, Mandal R, Biswas MC, Ghosh A, Mitra A, Boler AK. Iris naevus (Cogan-Reese) syndrome. J Indian Med Assoc 2008 August;106(8):538.
59. Sen HN, Bodaghi B, Hoang PL, Nussenblatt R. Primary intraocular lymphoma: diagnosis and differential diagnosis. Ocul Immunol Inflamm 2009 May;17(3):133-41.
60. Sen J, Clewes AR, Quah SA, Hiscott PS, Bucknall RC, Damato BE. Presymptomatic diagnosis of bronchogenic carcinoma associated with bilateral diffuse uveal melanocytic proliferation. Clin Experiment Ophthalmol 2006 March;34(2):156-8.
61. Sharma P, Shields CL, Turaka K, Eagle RC, Jr., Shields JA. Ciliary body medulloepithelioma with neoplastic cyclitic membrane imaging with fluorescein angiography and ultrasound biomicroscopy. Graefes Arch Clin Exp Ophthalmol 2011 April;%20.
62. Shields CL, Benevides R, Materin MA, Shields JA. Optical coherence tomography of retinal astrocytic hamartoma in 15 cases. Ophthalmology 2006 September;113(9):1553-7.
63. Shields CL, Mashayekhi A, Ho T, Cater J, Shields JA. Solitary congenital hypertrophy of the retinal pigment epithelium: clinical features and frequency of enlargement in 330 patients. Ophthalmology 2003 October;110(10):1968-76.
64. Shields CL, Materin MA, Mehta S, Foxman BT, Shields JA. Regression of extrafoveal choroidal osteoma following photodynamic therapy. Arch Ophthalmol 2008 January;126(1):135-7.
65. Shields CL, Pirondini C, Bianciotto C, Harmon SA, Shields JA. Autofluorescence of congenital hypertrophy of the retinal pigment epithelium. Retina 2007 October;27(8):1097-100.
66. Shields CL, Sun H, Demirci H, Shields JA. Factors predictive of tumor growth, tumor decalcification, choroidal neovascularization, and visual outcome in 74 eyes with choroidal osteoma. Arch Ophthalmol 2005 December;123(12):1658-66.
67. Shields CL, Thangappan A, Hartzell K, Valente P, Pirondini C, Shields JA. Combined hamartoma of the retina and retinal pigment epithelium in 77 consecutive patients visual outcome based on macular versus extramacular tumor location. Ophthalmology 2008 December;115(12):2246-52.
68. Shields JA, Eagle RC, Jr., Shields CL, Brown GC, Lally SE. Malignant transformation of congenital hypertrophy of the retinal pigment epithelium. Ophthalmology 2009 November;116(11):2213-6.
69. Shields JA, Mashayekhi A, Ra S, Shields CL. Pseudomelanomas of the posterior uveal tract: the 2006 Taylor R. Smith Lecture. Retina 2005 September;25(6):767-71.
70. Shuin T, Yamasaki I, Tamura K, Okuda H, Furihata M, Ashida S. Von Hippel-Lindau disease: molecular pathological basis, clinical criteria, genetic testing, clinical features of tumors and treatment. Jpn J Clin Oncol 2006 June;36(6):337-43.
71. Singh AD, Kaiser PK, Sears JE. Choroidal hemangioma. Ophthalmol Clin North Am 2005 March;18(1):151-61, ix.
72. Song WK, Byeon SH, Kim SS, Kwon OW, Lee SC. Gamma knife radiosurgery for choroidal haemangiomas with extensive exudative retinal detachment. Br J Ophthalmol 2009 June;93(6):836-7.
73. Song WK, Koh HJ, Kwon OW, Byeon SH, Lee SC. Intravitreal bevacizumab for choroidal neovascularization secondary to choroidal osteoma. Acta Ophthalmol 2009 February;87(1):100-1.
74. Soysal HG. Metastatic tumors of the uvea in 38 eyes. Can J Ophthalmol 2007 December;42(6):832-5.
75. Swann PG. Iris mammillations in ocular melanocytosis. Clin Exp Optom 2001 January;84(1):35-8.
76. Taban M, Sears JE, Singh AD. Ciliary body naevus. Eye (Lond) 2007 December;21(12):1528-30.
77. Torres VL, Brugnoni N, Kaiser PK, Singh AD. Optical coherence tomography enhanced depth imaging of choroidal tumors. Am J Ophthalmol 2011 April;151(4):586-93.
78. Trichopoulos N, Augsburger JJ. Neuroendocrine tumors metastatic to the uvea: diagnosis by fine needle aspiration biopsy. Graefes Arch Clin Exp Ophthalmol 2006 April;244(4):524-8.
79. Tsipursky MS, Golchet PR, Jampol LM. Photodynamic therapy of choroidal hemangioma in sturge-weber syndrome, with a review of treatments for diffuse and circumscribed choroidal hemangiomas. Surv Ophthalmol 2011 January;56(1):68-85.
80. Turell ME, Singh AD. Vascular tumors of the retina and choroid: diagnosis and treatment. Middle East Afr J Ophthalmol 2010 July;17(3):191-200.
81. Vrabec TR, Augsburger JJ. Exudative retinal detachment due to small noncalcified retinal astrocytic hamartoma. Am J Ophthalmol 2003 November;136(5):952-4.
82. Wackernagel W, Lackner EM, Pilz S, Mayer C, Stepan V. von Hippel-Lindau disease: treatment of retinal haemangioblastomas by targeted therapy with systemic bevacizumab. Acta Ophthalmol 2010 November;88(7):e271-e272.
83. Wong WT, Agron E, Coleman HR et al. Clinical characterization of retinal capillary hemangioblastomas in a large population of patients with von Hippel-Lindau disease. Ophthalmology 2008 January;115(1):181-8.
84. Wong WT, Liang KJ, Hammel K, Coleman HR, Chew EY. Intravitreal ranibizumab therapy for retinal capillary hemangioblastoma related to von Hippel-Lindau disease. Ophthalmology 2008 November;115(11):1957-64.
85. Yeh S, Weichel ED, Faia LJ et al. 25-Gauge transconjunctival sutureless vitrectomy for the diagnosis of intraocular lymphoma. Br J Ophthalmol 2010 May;94(5):633-8.
86. Zhang X, Dong F, Dai R, Yu W. Surgical management of epiretinal membrane in combined hamartomas of the retina and retinal pigment epithelium. Retina 2010 February;30(2):305-9.

Melanocytic Conjunctival Lesions
1. Ackerman AB, Sood R, Koenig M. Primary acquired melanosis of the conjunctiva is melanoma in situ. Mod Pathol 1991 March;4(2):253-63.
2. Anandajeya WV, Correa ZM, Augsburger JJ. Primary acquired melanosis with atypia treated with mitomycin C. Int Ophthalmol 2009 August;29(4):285-8.
3. Anastassiou G, Heiligenhaus A, Bechrakis N, Bader E, Bornfeld N, Steuhl KP. Prognostic value of clinical and histopathological parameters in conjunctival melanomas: a retrospective study. Br J Ophthalmol 2002 February;86(2):163-7.
4. Busam KJ, Fang Y, Jhanwar SC, Pulitzer MP, Marr B, Abramson DH. Distinction of conjunctival melanocytic nevi from melanomas by fluorescence in situ hybridization. J Cutan Pathol 2010 February;37(2):196-203.
5. Dalla PG, Ghirlando A, Busato F, Midena E. Reconstruction of conjunctiva with amniotic membrane after excision of large conjunctival melanoma: a long-term study. Eur J Ophthalmol 2005 July;15(4):446-50.
6. Damato B, Coupland SE. Conjunctival melanoma and melanosis: a reappraisal of terminology, classification and staging. Clin Experiment Ophthalmol 2008 November;36(8):786-95.
7. Damato B, Coupland SE. An audit of conjunctival melanoma treatment in Liverpool. Eye (Lond) 2009 April;23(4):801-9.
8. Damato B, Coupland SE. Management of conjunctival melanoma. Expert Rev Anticancer Ther 2009 September;9(9):1227-39.
9. Demirci H, McCormick SA, Finger PT. Topical mitomycin chemotherapy for conjunctival malignant melanoma and primary acquired melanosis with atypia: clinical experience with histopathologic observations. Arch Ophthalmol 2000 July;118(7):885-91.
10. Demirci H, Shields CL, Bianciotto CG, Shields JA. Topical imiquimod for periocular lentigo maligna. Ophthalmology 2010 December;117(12):2424-9.
11. Desjardins L, Poncet P, Levy C, Schlienger P, Asselain B, Validire P. [Prognostic factors in malignant melanoma of the conjunctiva. An anatomo-clinical study of 56 patients]. J Fr Ophtalmol 1999 April;22(3):315-21.
12. Dratviman-Storobinsky O, Cohen Y, Frenkel S, Pe'er J, Goldenberg-Cohen N. Lack of oncogenic GNAQ mutations in melanocytic lesions of the conjunctiva as compared to uveal melanoma. Invest Ophthalmol Vis Sci 2010 December;51(12):6180-2.
13. Folberg R, McLean IW, Zimmerman LE. Conjunctival melanosis and melanoma. Ophthalmology 1984 June;91(6):673-8.
14. Folberg R, McLean IW, Zimmerman LE. Malignant melanoma of the conjunctiva. Hum Pathol 1985 February;16(2):136-43.
15. Fuchs U, Kivela T, Liesto K, Tarkkanen A. Prognosis of conjunctival melanomas in relation to histopathological features. Br J Cancer 1989 February;59(2):261-7.
16. Goldenberg-Cohen N, Cohen Y, Rosenbaum E et al. T1799A BRAF mutations in conjunctival melanocytic lesions. Invest Ophthalmol Vis Sci 2005 September;46(9):3027-30.
17. Groh MJ, Holbach LM, Kuhnel B, Conway RM, Naumann GO. [Management of conjunctival malignant melanoma associated with primary acquired melanosis (PAM) using 0.02% mitomycin C eyedrops]. Ophthalmologe 2003 September;100(9):708-12.
18. Harooni H, Schoenfield LR, Singh AD. Current appraisal of conjunctival melanocytic tumors: classification and treatment. Future Oncol 2011 March;7(3):435-46.
19. Heegaard S, Jensen OA, Prause JU. Immunohistochemical diagnosis of malignant melanoma of the conjunctiva and uvea: comparison of the novel antibody against melan-A with S100 protein and HMB-45. Melanoma Res 2000 August;10(4):350-4.
20. Jakobiec FA. The ultrastructure of conjunctival melanocytic tumors. Trans Am Ophthalmol Soc 1984;82:599-752.:599-752.
21. Jay V, Font RL. Conjunctival amelanotic malignant melanoma arising in primary acquired melanosis sine pigmento. Ophthalmology 1998 January;105(1):191-4.
22. Kim JW, Abramson DH. Topical treatment options for conjunctival neoplasms. Clin Ophthalmol 2008 September;2(3):503-15.
23. Lichtinger A, Pe'er J, Frucht-Pery J, Solomon A. Limbal stem cell deficiency after topical mitomycin C therapy for primary acquired melanosis with atypia. Ophthalmology 2010 March;117(3):431-7.
24. Liesegang TJ. Pigmented conjunctival and scleral lesions. Mayo Clin Proc 1994 February;69(2):151-61.
25. McDonnell JM, Carpenter JD, Jacobs P, Wan WL, Gilmore JE. Conjunctival melanocytic lesions in children. Ophthalmology 1989 July;96(7):986-93.
26. Messmer EM, Mackert MJ, Zapp DM, Kampik A. In vivo confocal microscopy of pigmented conjunctival tumors. Graefes Arch Clin Exp Ophthalmol 2006 November;244(11):1437-45.
27. Missotten GS, Keijser S, de Keizer RJ, Wolff-Rouendaal D. Conjunctival melanoma in the Netherlands: a nationwide study. Invest Ophthalmol Vis Sci 2005 January;46(1):75-82.
28. Pe'er J, Frucht-Pery J. The treatment of primary acquired melanosis (PAM) with atypia by topical Mitomycin C. Am J Ophthalmol 2005 February;139(2):229-34.
29. Sandinha T, Russell H, Kemp E, Roberts F. Malignant melanoma of the conjunctiva with intraocular extension: a clinicopathological study of three cases. Graefes Arch Clin Exp Ophthalmol 2007 March;245(3):431-6.
30. Savar A, Ross MI, Prieto VG, Ivan D, Kim S, Esmaeli B. Sentinel lymph node biopsy for ocular adnexal melanoma: experience in 30 patients. Ophthalmology 2009 November;116(11):2217-23.
31. Sharara NA, Alexander RA, Luthert PJ, Hungerford JL, Cree IA. Differential immunoreactivity of melanocytic lesions of the conjunctiva. Histopathology 2001 October;39(4):426-31.
32. Shields CL, Demirci H, Karatza E, Shields JA. Clinical survey of 1643 melanocytic and nonmelanocytic conjunctival tumors. Ophthalmology 2004 September;111(9):1747-54.
33. Shields CL, Fasiuddin AF, Mashayekhi A, Shields JA. Conjunctival nevi: clinical features and natural course in 410 consecutive patients. Arch Ophthalmol 2004 February;122(2):167-75.
34. Shields CL, Shields JA. Tumors of the conjunctiva and cornea. Surv Ophthalmol 2004 January;49(1):3-24.
35. Shields CL, Shields JA. Conjunctival tumors in children. Curr Opin Ophthalmol 2007 September;18(5):351-60.
36. Shields CL, Shields JA, Armstrong T. Management of conjunctival and corneal melanoma with surgical excision, amniotic membrane allograft, and topical chemotherapy. Am J Ophthalmol 2001 October;132(4):576-8.
37. Shields JA, Shields CL, De PP. Surgical management of circumscribed conjunctival melanomas. Ophthal Plast Reconstr Surg 1998 May;14(3):208-15.
38. Shields JA, Shields CL, Luminais S, Eagle RC, Jr. Differentiation of pigmented conjunctival squamous cell carcinoma from melanoma. Ophthalmic Surg Lasers Imaging 2003 September;34(5):406-8.
39. Shields JA, Shields CL, Mashayekhi A et al. Primary acquired melanosis of the conjunctiva: experience with 311 eyes. Trans Am Ophthalmol Soc 2007;105:61-71; discussion 71-2.:61-71.
40. Shields JA, Shields CL, Mashayekhi A et al. Primary acquired melanosis of the conjunctiva: risks for progression to melanoma in 311 eyes. The 2006 Lorenz E. Zimmerman lecture. Ophthalmology 2008 March;115(3):511-9.
41. Shildkrot Y, Wilson MW. Conjunctival melanoma: pitfalls and dilemmas in management. Curr Opin Ophthalmol 2010 September;21(5):380-6.
42. Steuhl KP, Rohrbach JM, Knorr M, Thiel HJ. Significance, specificity, and ultrastructural localization of HMB-45 antigen in pigmented ocular tumors. Ophthalmology 1993 February;100(2):208-15.
43. Sugiura M, Colby KA, Mihm MC, Jr., Zembowicz A. Low-risk and high-risk histologic features in conjunctival primary acquired melanosis with atypia: Clinicopathologic analysis of 29 cases. Am J Surg Pathol 2007 February;31(2):185-92.
44. Tatla T, Hungerford J, Plowman N, Ghufoor K, Keene M. Conjunctival melanoma: the role of conservative surgery and radiotherapy in regional metastatic disease. Laryngoscope 2005 May;115(5):817-22.
45. Tuomaala S, Aine E, Saari KM, Kivela T. Corneally displaced malignant conjunctival melanomas. Ophthalmology 2002 May;109(5):914-9.
46. Tuomaala S, Kivela T. Sentinel lymph node biopsy guidelines for conjunctival melanoma. Melanoma Res 2008 June;18(3):235.
47. Walsh-Conway N, Conway RM. Plaque brachytherapy for the management of ocular surface malignancies with corneoscleral invasion. Clin Experiment Ophthalmol 2009 August;37(6):577-83.
48. Wuestemeyer H, Sauerwein W, Meller D et al. Proton radiotherapy as an alternative to exenteration in the management of extended conjunctival melanoma. Graefes Arch Clin Exp Ophthalmol 2006 April;244(4):438-46.

Squamous Cell Carcinoma
1. Berenbom A, Milman T, Finger PT. FIT biopsy for conjunctival squamous cell carcinoma with extensive intraocular invasion. Graefes Arch Clin Exp Ophthalmol 2008 March;246(3):467-9.
2. Caujolle JP, Maschi C, Chauvel P, Herault J, Gastaud P. [Surgery and additional protontherapy for treatment of invasive and recurrent squamous cell carcinomas: technique and preliminary results]. J Fr Ophtalmol 2009 December;32(10):707-14.
3. Char DH, Crawford JB. Orbital invasion despite topical anti-metabolite therapy for conjunctival carcinoma. Graefes Arch Clin Exp Ophthalmol 2008 March;246(3):459-61.
4. Esquenazi S, Fry CL, Holley E. Treatment of biopsy proved conjunctival intraepithelial neoplasia with topical interferon alfa-2b. Br J Ophthalmol 2005 September;89(9):1221.
5. Gupta N, Sachdev R, Tandon R. Ocular surface squamous neoplasia in xeroderma pigmentosum: clinical spectrum and outcome. Graefes Arch Clin Exp Ophthalmol 2011 April 12.
6. Heindl LM, Hofmann-Rummelt C, Adler W et al. Tumor-associated lymphangiogenesis in the development of conjunctival squamous cell carcinoma. Ophthalmology 2010 April;117(4):649-58.
7. Holcombe DJ, Lee GA. Topical interferon alfa-2b for the treatment of recalcitrant ocular surface squamous neoplasia. Am J Ophthalmol 2006 October;142(4):568-71.
8. Karcioglu ZA, Wagoner MD. Demographics, etiology, and behavior of conjunctival squamous cell carcinoma in the 21st century. Ophthalmology 2009 November;116(11):2045-6.
9. Karp CL, Galor A, Chhabra S, Barnes SD, Alfonso EC. Subconjunctival/perilesional recombinant interferon alpha2b for ocular surface squamous neoplasia: a 10-year review. Ophthalmology 2010 December;117(12):2241-6.
10. Khong JJ, Muecke J. Complications of mitomycin C therapy in 100 eyes with ocular surface neoplasia. Br J Ophthalmol 2006 July;90(7):819-22.
11. Khong JJ, Muecke J. Complications of mitomycin C therapy in 100 eyes with ocular surface neoplasia. Br J Ophthalmol 2006 July;90(7):819-22.
12. Kim JW, Abramson DH. Topical treatment options for conjunctival neoplasms. Clin Ophthalmol 2008 September;2(3):503-15.
13. Kim JW, Abramson DH. Topical treatment options for conjunctival neoplasms. Clin Ophthalmol 2008 September;2(3):503-15.
14. Manderwad GP, Kannabiran C, Honavar SG, Vemuganti GK. Lack of association of high-risk human papillomavirus in ocular surface squamous neoplasia in India. Arch Pathol Lab Med 2009 August;133(8):1246-50.
15. Nagaiah G, Stotler C, Orem J, Mwanda WO, Remick SC. Ocular surface squamous neoplasia in patients with HIV infection in sub-Saharan Africa. Curr Opin Oncol 2010 September;22(5):437-42.
16. Parrozzani R, Lazzarini D, Dario A, Midena E. In vivo confocal microscopy of ocular surface squamous neoplasia. Eye (Lond) 2011 April;25(4):455-60.
17. Parrozzani R, Lazzarini D, emany-Rubio E, Urban F, Midena E. Topical 1% 5-fluorouracil in ocular surface squamous neoplasia: a long-term safety study. Br J Ophthalmol 2011 March;95(3):355-9.
18. Pe'er J. Ocular surface squamous neoplasia. Ophthalmol Clin North Am 2005 March;18(1):1-13, vii.
19. Ramonas KM, Conway RM, Daftari IK, Crawford JB, O'Brien JM. Successful treatment of intraocularly invasive conjunctival squamous cell carcinoma with proton beam therapy. Arch Ophthalmol 2006 January;124(1):126-8.
20. Rudkin AK, Dodd T, Muecke JS. The differential diagnosis of localised amelanotic limbal lesions: a review of 162 consecutive excisions. Br J Ophthalmol 2011 March;95(3):350-4.
21. Rudkin AK, Muecke JS. Adjuvant 5-fluorouracil in the treatment of localised ocular surface squamous neoplasia. Br J Ophthalmol 2011 January;%20.
22. Sears KS, Rundle PR, Mudhar HS, Rennie IG. The effects of photodynamic therapy on conjunctival in situ squamous cell carcinoma--a review of the histopathology. Br J Ophthalmol 2008 May;92(5):716-7.
23. Shields CL, Manchandia A, Subbiah R, Eagle RC, Jr., Shields JA. Pigmented squamous cell carcinoma in situ of the conjunctiva in 5 cases. Ophthalmology 2008 October;115(10):1673-8.
24. Shields CL, Manchandia A, Subbiah R, Eagle RC, Jr., Shields JA. Pigmented squamous cell carcinoma in situ of the conjunctiva in 5 cases. Ophthalmology 2008 October;115(10):1673-8.
25. Shields JA, Eagle RC, Marr BP, Shields CL, Grossniklaus HE, Stulting RD. Invasive spindle cell carcinoma of the conjunctiva managed by full-thickness eye wall resection. Cornea 2007 September;26(8):1014-6.
26. Verma V, Shen D, Sieving PC, Chan CC. The role of infectious agents in the etiology of ocular adnexal neoplasia. Surv Ophthalmol 2008 July;53(4):312-31.
27. Walsh-Conway N, Conway RM. Plaque brachytherapy for the management of ocular surface malignancies with corneoscleral invasion. Clin Experiment Ophthalmol 2009 August;37(6):577-83.
28. Walsh-Conway N, Conway RM. Plaque brachytherapy for the management of ocular surface malignancies with corneoscleral invasion. Clin Experiment Ophthalmol 2009 August;37(6):577-83.

Other Conjunctival Tumors
1. Chan CC, Shen D, Mochizuki M et al. Detection of Helicobacter pylori and Chlamydia pneumoniae genes in primary orbital lymphoma. Trans Am Ophthalmol Soc 2006;104:62-70.:62-70.
2. Chao AN, Shields CL, Krema H, Shields JA. Outcome of patients with periocular sebaceous gland carcinoma with and without conjunctival intraepithelial invasion. Ophthalmology 2001 October;108(10):1877-83.
3. Charlotte F, Doghmi K, Cassoux N et al. Ocular adnexal marginal zone B cell lymphoma: a clinical and pathologic study of 23 cases. Virchows Arch 2006 April;448(4):506-16.
4. Coupland SE, Hellmich M, uw-Haedrich C, Lee WR, Stein H. Prognostic value of cell-cycle markers in ocular adnexal lymphoma: an assessment of 230 cases. Graefes Arch Clin Exp Ophthalmol 2004 February;242(2):130-45.
5. Coupland SE, White VA, Rootman J, Damato B, Finger PT. A TNM-based clinical staging system of ocular adnexal lymphomas. Arch Pathol Lab Med 2009 August;133(8):1262-7.
6. Coupland SE. Ocular adnexal lymphoid tumors: progress in need of clarification. Am J Ophthalmol 2008 November;146(5):791-2.
7. Esmaeli B, McLaughlin P, Pro B et al. Prospective trial of targeted radioimmunotherapy with Y-90 ibritumomab tiuxetan (Zevalin) for front-line treatment of early-stage extranodal indolent ocular adnexal lymphoma. Ann Oncol 2009 April;20(4):709-14.
8. Farmer JP, Lamba M, Merkur AB et al. Characterization of lymphoproliferative lesions of the conjunctiva: immunohistochemical and molecular genetic studies. Can J Ophthalmol 2006 December;41(6):753-60.
9. Ferreri AJ, Dolcetti R, Du MQ et al. Ocular adnexal MALT lymphoma: an intriguing model for antigen-driven lymphomagenesis and microbial-targeted therapy. Ann Oncol 2008 May;19(5):835-46.
10. Ferreri AJ, Govi S, Colucci A, Crocchiolo R, Modorati G. Intralesional rituximab: a new therapeutic approach for patients with conjunctival lymphomas. Ophthalmology 2011 January;118(1):24-8.
11. Ferry JA, Fung CY, Zukerberg L et al. Lymphoma of the ocular adnexa: A study of 353 cases. Am J Surg Pathol 2007 February;31(2):170-84.
12. Ho VH, Ross MI, Prieto VG, Khaleeq A, Kim S, Esmaeli B. Sentinel lymph node biopsy for sebaceous cell carcinoma and melanoma of the ocular adnexa. Arch Otolaryngol Head Neck Surg 2007 August;133(8):820-6.
13. Jakobiec FA. Ocular adnexal lymphoid tumors: progress in need of clarification. Am J Ophthalmol 2008 June;145(6):941-50.
14. Lagoo AS, Haggerty C, Kim Y et al. Morphologic features of 115 lymphomas of the orbit and ocular adnexa categorized according to the World Health Organization classification: are marginal zone lymphomas in the orbit mucosa-associated lymphoid tissue-type lymphomas? Arch Pathol Lab Med 2008 September;132(9):1405-16.
15. Lee SE, Paik JS, Cho WK et al. Feasibility of the TNM-based staging system of ocular adnexal extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma). Am J Hematol 2011 March;86(3):262-6.
16. Levecq L, De PP, Jamart J. Conjunctival nevi clinical features and therapeutic outcomes. Ophthalmology 2010 January;117(1):35-40.
17. Lommatzsch PK, Willerding G, Nenning H, Taubert G. [Inflammatory juvenile conjunctival nevus (IJCN)]. Klin Monbl Augenheilkd 2007 May;224(5):422-6.
18. Minoda H, Usui N, Sata T, Katano H, Serizawa H, Okada S. Human herpesvirus-8 in Kaposi's sarcoma of the conjunctiva in a patient with AIDS. Jpn J Ophthalmol 2006 January;50(1):7-11.
19. Reiser BJ, Mok A, Kukes G, Kim JW. Non-AIDS-related Kaposi sarcoma involving the tarsal conjunctiva and eyelid margin. Arch Ophthalmol 2007 June;125(6):838-40.
20. Rishi K, Font RL. Sebaceous gland tumors of the eyelids and conjunctiva in the Muir-Torre syndrome: a clinicopathologic study of five cases and literature review. Ophthal Plast Reconstr Surg 2004 January;20(1):31-6.
21. Robinson L, McKellar M, Fitzharris B, Elder M. Topical mitomycin C for the local treatment of a primary diffuse large B-cell lymphoma of the palpebral conjunctiva. Clin Experiment Ophthalmol 2009 December;37(9):891-2.
22. Rudkin AK, Muecke JS. Mitomycin-C as adjuvant therapy in the treatment of sebaceous gland carcinoma in high-risk locations. Clin Experiment Ophthalmol 2009 May;37(4):352-6.
23. Shields CL, Fasiuddin AF, Mashayekhi A, Shields JA. Conjunctival nevi: clinical features and natural course in 410 consecutive patients. Arch Ophthalmol 2004 February;122(2):167-75.
24. Shields CL, Naseripour M, Shields JA, Eagle RC, Jr. Topical mitomycin-C for pagetoid invasion of the conjunctiva by eyelid sebaceous gland carcinoma. Ophthalmology 2002 November;109(11):2129-33.
25. Shields CL, Shields JA. Conjunctival tumors in children. Curr Opin Ophthalmol 2007 September;18(5):351-60.
26. Shields CL, Shields JA. Tumors of the conjunctiva and cornea. Surv Ophthalmol 2004 January;49(1):3-24.
27. Shields JA, Demirci H, Marr BP, Eagle RC, Jr., Stefanyszyn M, Shields CL. Conjunctival epithelial involvement by eyelid sebaceous carcinoma. The 2003 J. Howard Stokes lecture. Ophthal Plast Reconstr Surg 2005 March;21(2):92-6.
28. Sjo LD. Ophthalmic lymphoma: epidemiology and pathogenesis. Acta Ophthalmol 2009 February;87 Thesis 1:1-20.:1-20.
29. Son SH, Choi BO, Kim GW et al. Primary radiation therapy in patients with localized orbital marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT Lymphoma). Int J Radiat Oncol Biol Phys 2010 May 1;77(1):86-91.
30. Sullivan TJ, Whitehead K, Williamson R et al. Lymphoproliferative disease of the ocular adnexa: a clinical and pathologic study with statistical analysis of 69 patients. Ophthal Plast Reconstr Surg 2005 May;21(3):177-88.
31. Thiagalingam S, Johnson MM, Colby KA, Zembowicz A. Juvenile conjunctival nevus: clinicopathologic analysis of 33 cases. Am J Surg Pathol 2008 March;32(3):399-406.
32. Verma V, Shen D, Sieving PC, Chan CC. The role of infectious agents in the etiology of ocular adnexal neoplasia. Surv Ophthalmol 2008 July;53(4):312-31.

XIV. Low Vision Rehabilitation

Basic Information
1. American Academy of Ophthalmology Preferred Practice Patterns Committee. Preferred Practice Pattern® Guidelines. Vision Rehabilitation for Adults. American Academy of Ophthalmology. 2nd printing 2010. Available at: http://www.aao.org/ppp.
2. Congdon N, O'Colmain B, Klaver CC, et al. Causes and prevalence of visual impairment among adults in the United States. Arch Ophthalmol 2004;122:477-85.
3. Faye EE, Chan-O’Connell, L, Fischer M, Freed B, Pang, L, Rosenthal B. The Lighthouse Clinican’s Guide to Low Vision Practice. New York: Lighthouse International; 2011.

Additional Sources
1. Brown GC, Brown MM, Sharma S. Differences between ophthalmologists’ and patients’ perception of quality of life associated with macular degeneration. Can J Ophthal 2000;35:127-33.
2. Canadian Journal of Ophthalmology Special Issue on Low Vision Rehabilitation, June 2006, Ed: Markowitz, SN. http://pubs.nrc-cnrc.gc.ca/cjo/cho41-03.html.
3. Crane WG, Fletcher DC, Schuchard RA. Prevalence of photopsias and Charles Bonnet Syndrome in a low vision population. Ophthalmol Clin North Am 1994;7:143-9.clinic. Br J Ophthalmol 2007;91:296-8.
4. Goodrich GL, Arditi A  Low Vision: The Reference – A bibliographic datavbase that currently contains 11,900 references on Low Vision. Available at: www.lvtr.info/
5. Jackson AJ, Wolffsohn JS, Bailey IL. Low Vision Manual. Philadelphia, Penn:Elsevier, 2007.
6. Markowitz SN, Muller C. Macular perimetry in low vision. Can J Ophthal 2004;39:56-60.
7. Massof RW, Lidoff L, eds. Issues in Low Vision Rehabilitation. Service Delivery, policy and Funding. New York: AFB Press, 2001.
8. Mogk LG, Mogk M. Macular Degeneration: The Complete Guide to Saving and Maximizing Your Sight. New York: Ballantine Books; 2003.
9. Rosenthal BP, Cole RG, London R. Functional Assessment of Low Vision. St. Louis, MO: Mosby, 1996.
10. Faye E.E.: Clinical low vision (2nd. ed.). Boston; Little, Brown, 1984
11. Visual disturbances and blindness (H53-H54), In: International Statistical Classification of Diseases and Related Health Problems. WHO, 10th Revision, Version for 2007. See on-line: http://apps.who.int/classifications/apps/icd/icd10online/

Additional Papers (after 2000)
1. Biousse V, Skibell BC, Watts RL, et al. Ophthalmologic features of Parkinson's disease. Neurology 2004;62:177-80.
2. de Boer MR, Pluijm SM, Lips P, et al. Different aspects of visual impairment as risk factors for falls and fractures in older men and women. J Bone Miner Res 2004;19:1539-47.
4. Dhital A, Pey T, Stanford MR. Visual loss and falls: a review. Eye (Lond). 2010 24(9):1437-46
5. Gogate P, Rishikeshi N, Mehata R, Ranade S, Kharat J, Deshpande M. Visual impairment in the hearing impaired students. Indian J Ophthalmol. 2009 Nov-Dec;57(6):451-3.
6. Hassell JB, Lamoureux EL, Keeffe JE. Impact of age related macular degeneration on quality of life. Br J Ophthalmol 2006; 90: 593-596
7. Horowitz A. Vision impairment and functional disability among nursing home residents. Gerontologist 1994;34:316-23.
8. Jackson ML, Bassett K, Nirmalan PV, Sayre EC. Contrast sensitivity and visual hallucinations in patients referred to a low vision rehabilitation. Br J Ophthalmol 2007;91:296-298.
9. Johnson L, Buckley JG, Scally AJ, Elliott DB. Multifocal spectacles increase variability in toe clearance and risk of tripping in the elderly. Invest Ophthalmol Vis Sci 2007;48:1466-71.
10. Lee PP, Spritzer K, Hays RD. The impact of blurred vision on functioning and well being. Ophthalmology 1997;104:390-6.
11. Lord SR, Dayhew J, Howland A. Multifocal glasses impair edge-contrast sensitivity and depth perception and increase the risk of falls in older people. J Am Geriatr Soc 2002;50:1760-6.
12. Owsley C, Sloane ME. Contrast sensitivity, acuity, and the perception of 'real-world' targets. Br J Ophthalmol 1987;71:791-6.
13. Pollard TL, Simpson JA, Lamoureux EL, Keeffe JE. Barriers to accessing low vision services. Ophthalmic Physiol Opt 2003;23:321-7.
14. Riordan-Eva P, Cunningham E (Eds). Vaughan & Asbury's General Ophthalmology, Lange Clinical Medicine
15. Scott IU, Smiddy WE, Schiffman J, et al. Quality of life of low-vision patients and the impact of low-vision services. Am J Ophthalmol 1999;128:54-62.
16. Shaaban S, El-Lakkany AR, Swelam A, Anwar G. Low vision AIDS provision for visually impaired egyptian patients - a clinical outcome. Middle East Afr J Ophthalmol. 2009 Jan;16(1):29-34.
17. Stelmack JA, Rosenbloom AA, Brenneman CS, Stelmack TR. Patients' perceptions of the need for low vision devices. J Vis Impair Blind 2003;97:521-35.
18. Stelmack JA, Tang SC, Reda DF et al. Outcomes of the Veterans Affairs Low Vision Intervention Trial (LOVIT). Arch Ophthalmol 2008;126:608-17.
19. Trauzettel-Klosinski, S. Rehabilitation for visual disorders. J Neuro-Ophthalmol 2010; 30: 73-84
20. Wang JJ, Mitchell P, Smith W, Leeder SR. Factors associated with use of community support services in an older Australian population. Aust N Z J Public Health 1999;23:147-53.
21. Warren, M. Barstow, B. Occupational Therapy interventions for Adults with Low Vision. AOTA Press. 2010
22. West SK, Munoz B, Rubin GS, et al. Function and visual impairment in a population-based study of older adults. The SEE project. Salisbury Eye Evaluation. Invest Ophthalmol Vis Sci 1997;38:72-82.
23. West SK, Rubin GS, Broman AT, et al. How does visual impairment affect performance on tasks of everyday life? The SEE Project. Salisbury Eye Evaluation. Arch Ophthalmol 2002;120:774-80.
24. Wolter M, Preda S. Visual deficits following stroke: maximizing participation in rehabilitation. Top Stroke Rehabil 2006;13:12-21.

XV. Ethics and Professionalism in Ophthalmology

Medical Ethics Documents
1. The Hippocratic Oath
http://www.nlm.nih.gov/hmd/greek/greek_oath.html
2. WMA Declaration of Geneva
http://www.wma.net/en/30publications/10policies/g1/
3. Ethical Code, International Council of Ophthalmology
www.icoph.org/pdf/icoethicalcode.pdf
4. Code of Ethics, American Academy of Ophthalmology
5. Nuremburg Code
http://ohsr.od.nih.gov/guidelines/nuremberg.html
6. WMA Declaration of Helsinki
http://www.wma.net/en/30publications/10policies/b3/
7. Belmont Report

Suggested Additional Reading
1. Angell, M. The Truth About Drug Companies, How They Deceive Us and What to Do About It. New York, Random House, 2005
2. Gawande A. Better: A Surgeon's Notes on Performance. New York. Metropolitan Books, 2010
3. Harbin T. Waking up Blind - Lawsuits Over Eye Surgery. Minneapolis, Langdon Street Press 2009
4. Kassirer J. On The Take: How Medicine’s Complicity With Big Business Can Endanger Your Health. New York, Oxford University Press, 2004

XVI. Community Eye Health
1.      Johnson G (editor). The epidemiology of eye disease. Third edition. Arnold. 2011. 
2.      World Health Organization: Action plan for the prevention of avoidable blindness and visual impairment 2009–2013. [Available from: http://www.who.int/entity/blindness/ACTION_PLAN_WHA62-1-English.pdf]
 3.      World Health Organization. Universal eye health: a global action plan 2014–2019. [Available from: http://www.who.int/blindness/actionplan/en/]
4.      World Sight Day report 2013: towards universal eye health. International Agency for the Prevention of Blindness, 2013. 
5.      Stevens GA, White RA, Flaxman SR et al. Global prevalence of visual impairment and blindness – Magnitude and temporal trends  1990-2010. Ophthalmology 2013; 120: 2377-2384. 
6.      Pascolini SD, Mariotti SP. Global estimates of visual impairment: Br J Ophthalmol 2012;96: 614-618.
 7.   Global data on visual impairment in the year 2002. Bulletin of the World Health Organization; November 2004; 844–851. [Available from: http://www.who.int/bulletin/volumes/82/11/en/844.pdf]
9.  Inclusion Made Easy in Eye Health Programs. [Available from: cbm.org/disability-inclusive-eye-health]
10. Facing up to Disability. Community Eye Health Journal, Volume 26, Issue 81, 2013. [Available from: http://www.cehjournal.org/wp-content/uploads/facing-up-to-disability.pdf]
11. The Economic Costs of Exclusion and Gains of Inclusion of People with Disabilities. Evidence from Low and Middle Income Countries. Lena Morgan Banks and Sarah Polock. [Available from: http://www.iapb.org/sites/iapb.org/files/CBM_Costs%20of%20Exclusion%20and%20Gains%20of%20Inclusion%20Report_2015.pdf]



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